Protein Alignment Nep4 and ecel1

DIOPT Version :10

• Sequence 1: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_001429584.1
• Gene: ecel1 / 100332538
• ZFINID: ZDB-GENE-130530-692
• Length: 808
• Species: Danio rerio
• Alignment Length: 793
• Identity: 261/793 - (32%)
• Similarity: 388/793 - (48%)
• Gaps: 134/793 - (16%)

  Fly   263 AKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHS 327
            |:.::..:|..|.||.|||.:|||.|.|.|.||:||..:.....:.|.
Zfish   135 ARFVQGNIDPSVQPCHDFYSFACGGWLRRHGIPEDKLSYGIITAIGEQ----------------- 182

  Fly   328 AAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRK 392
                                                                       |..|.:
Zfish   183 -----------------------------------------------------------NQDKLQ 188

  Fly   393 RLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAV 457
            ||::.|.:|.:.|                                  .|:.|.|..||||:|...
Zfish   189 RLLQAPVQRRELE----------------------------------SAERKVKEFYRSCINIKE 219

  Fly   458 LAKRGLEPLHTLIRELGGW-----PVLESQWSES------NFNWQVLAATLRRYNNDILIVQWVG 511
            :.:.|..|:..:|...|||     |...:.|...      :|| ::|..|...|:..:.....|.
Zfish   220 IDRLGAGPMTEVIDSCGGWDLSGAPPGGAGWDSGSAPIRPDFN-EMLYKTQGVYSTSVFFSLTVS 283

  Fly   512 ADIKNSEENIVQFDQTGLGLPTREYFL--QPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASEL 574
            .|.|||..|.::.||.||.||.|..:|  ...:.|.|.:|:..|..::..:||..|..:  :.|:
Zfish   284 VDDKNSSRNAIRIDQEGLTLPERTLYLGQDEDSVKILASYKALMERLLSMLGAHNATLK--SREI 346

  Fly   575 VAFETQLAGITAP--AEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYA 637
            :..||:||.||..  .:||.:::.:|.|:||.|||.:.|...|:..|..:.:......||:|:.|
Zfish   347 LDLETKLANITVSEYEDQRKDISSMYNRITLKQLQKMAPSFHWKRLLDRIFNDNFSEEEEIVVLA 411

  Fly   638 VEYMSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIA 702
            .:||..:..::..|..|.:.|||:||.|.....::...|......|...:.|.|:.....::|:.
Zfish   412 TDYMQTVSDIIKTTSKRVLHNYMLWRMVAALSEHLSTAFRSTIHEFSREIDGTEQQLDLERLCLT 476

  Fly   703 QVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSL 767
            |.|.:.|||:|::||.::|.::|:.....:..|::.:....|:..||:|:.||..|..|:..|.:
Zfish   477 QANKHFGMALGALFVQQHFSSSSRAKVQELVEDIKHSLDVRLQELDWMDEETKDAARGKLQHMMV 541

  Fly   768 KIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNA 832
            ..|||||:|.|..::.:|| .::..:.||:|.||.:.:..|....|:|:.|:||.|...|..:||
Zfish   542 MTGYPDFLLKPELIDEEYA-FDVNEKTYFKNILNSIKYNIKLSIKKIHKEVDKTTWLLPPQALNA 605

  Fly   833 YYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTD 897
            ||..||||::||||||||..|...||:|||:||||.:||||||||:||.|..:||.||:.:|||:
Zfish   606 YYLPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGAIIGHELTHGYDDWGGQYDRYGNLKQWWTE 670

  Fly   898 SSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVSD 962
            .|.|.|.::..||:..|.|:||....:  ||..|.||||||.|||:.::||||:|::||..|
Zfish   671 ESYRKFQKKTECIVKLYDNFTVYNQRV--NGRLTLGENIADLGGLKLSYHAYQKWVREHGPE--- 730

  Fly   963 EILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPL 1027
            ..||||..|..||||:.|.|.||...|.::|..:|.|..|:|..:||||::|...:|.|.|:||.
Zfish   731 RPLPGLKHTHEQLFFIAFAQNWCMKRRSQSIYLQLLTDKHAPEHYRVIGSVSQFEEFGRVFHCPR 795

  Fly  1028 GSPMNPQKKCSVW 1040
            ||||||..|||||
Zfish   796 GSPMNPVNKCSVW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep4	NP_650904.3	M13	274..1038	CDD:341056	255/778 (33%)
ecel1	NP_001429584.1	None