Protein Alignment Lrrk and AT2G25790

DIOPT Version :9

• Sequence 1: NP_001262772.1
• Gene: Lrrk / 42447
• FlyBaseID: FBgn0038816
• Length: 2513
• Species: Drosophila melanogaster
• Sequence 2: NP_180150.1
• Gene: AT2G25790 / 817121
• AraportID: AT2G25790
• Length: 960
• Species: Arabidopsis thaliana
• Alignment Length: 652
• Identity: 149/652 - (22%)
• Similarity: 241/652 - (36%)
• Gaps: 206/652 - (31%)

  Fly   469 INKKGLPTPVEVNVFLPSTSNISYSAMFPNNPTIIDWHSMGSSVQLSVVRVPWMVSGVLLLNPKL 533
            ::...|..|:..::|..|:.::.|..:..||                       .||
plant   104 LSNNNLSGPIPHDIFTTSSPSLRYLNLSNNN-----------------------FSG-------- 137

  Fly   534 QSHPRLNEVALTAITRIDFSHNVLTSIPQELFHLV----SLRYLNVAQNKIT-DLPAPIGQTYGC 593
             |.||   ..|..:..:|.|:|:.|.   |:::.:    :||.|::..|.:| .:|..:|   ..
plant   138 -SIPR---GFLPNLYTLDLSNNMFTG---EIYNDIGVFSNLRVLDLGGNVLTGHVPGYLG---NL 192

  Fly   594 PVLDELFLQDNQLT-TLPAAIFHLPALSILDVSNNKLQ-QLPFDLWRAPKLRELNVAFNLLRDLP 656
            ..|:.|.|..|||| .:|..:..:..|..:.:..|.|. ::|:.:.....|..|::.:|.|.. |
plant   193 SRLEFLTLASNQLTGGVPVELGKMKNLKWIYLGYNNLSGEIPYQIGGLSSLNHLDLVYNNLSG-P 256

  Fly   657 VPPMQTSSSLLSLDKL-------NLQSFEEPPSNKPRNVTQQRLTHRNLWSATLDITDNDMKWQH 714
            :||     ||..|.||       |..|.:.|||         ..:.:||.|  ||.:||.:..:.
plant   257 IPP-----SLGDLKKLEYMFLYQNKLSGQIPPS---------IFSLQNLIS--LDFSDNSLSGEI 305

  Fly   715 EQDLGDGKTAGVGSSQLSSLNI----ANNLFTSIP---AALPCLAV------------------- 753
            .:.:          :|:.||.|    :|||...||   .:||.|.|
plant   306 PELV----------AQMQSLEILHLFSNNLTGKIPEGVTSLPRLKVLQLWSNRFSGGIPANLGKH 360

  Fly   754 -NLTRLNMSYNSLR--------SMGHVTSY------------PA-----TLKQLDLSHNEISCWP 792
             |||.|::|.|:|.        ..||:|..            |:     :|:::.|.:|..|  .
plant   361 NNLTVLDLSTNNLTGKLPDTLCDSGHLTKLILFSNSLDSQIPPSLGMCQSLERVRLQNNGFS--G 423

  Fly   793 SLPR----------ITESDPHLLCYSCVQLPEGRDDDYKTASSKGSSSSATSFRASVLKSVCRHR 847
            .|||          :..|:.:|         :|..:.:.....:....|...|... |....|.:
plant   424 KLPRGFTKLQLVNFLDLSNNNL---------QGNINTWDMPQLEMLDLSVNKFFGE-LPDFSRSK 478

  Fly   848 RHLRLEALRTLI---LADNLLTRIQLSTDDATTLFNESEDADWS---VVGV-NRSKVIFPNLSML 905
            |..:|:..|..|   :...|:|            |.|..|.|.|   :.|| .|......||..|
plant   479 RLKKLDLSRNKISGVVPQGLMT------------FPEIMDLDLSENEITGVIPRELSSCKNLVNL 531

  Fly   906 DMT-NNCLKEIPASLHELSSLSVLNISGNVNITELPPHLGLLSRLWNLNTRGCLLQEPLRSMIES 969
            |:: ||...|||:|..|...||.|::|.|....|:|.:||.:..|..:|....||
plant   532 DLSHNNFTGEIPSSFAEFQVLSDLDLSCNQLSGEIPKNLGNIESLVQVNISHNLL---------- 586

  Fly   970 KKHKTMDIVGYLKSIYEDAQPYARMKLMVVGVAGIGKSTLLDLLRQGAGSG-SSSSSHRSRASEN 1033
              |.::...|            |.:.:....|.|     .:||..:.:.|| ......|.|::::
plant   587 --HGSLPFTG------------AFLAINATAVEG-----NIDLCSENSASGLRPCKVVRKRSTKS 632

  Fly  1034 HW 1035
            .|
plant   633 WW 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lrrk	NP_001262772.1	Ank_2	111..200	CDD:289560
		ANK	146..286	CDD:238125
		ANK repeat	146..177	CDD:293786
		Ank_4	179..232	CDD:290365
		ANK repeat	179..209	CDD:293786
		Ank_2	216..389	CDD:289560
		ANK	361..477	CDD:238125	1/7 (14%)
		ANK repeat	361..390	CDD:293786
		Ank_2	364..464	CDD:289560
		ANK repeat	406..435	CDD:293786
		ANK repeat	437..464	CDD:293786
		LRR_8	<544..580	CDD:290566	10/39 (26%)
		leucine-rich repeat	547..569	CDD:275380	5/25 (20%)
		LRR_8	569..629	CDD:290566	17/61 (28%)
		leucine-rich repeat	570..595	CDD:275380	7/25 (28%)
		leucine-rich repeat	596..618	CDD:275380	8/22 (36%)
		leucine-rich repeat	619..641	CDD:275380	4/22 (18%)
		leucine-rich repeat	642..676	CDD:275380	13/40 (33%)
		leucine-rich repeat	677..730	CDD:275380	10/52 (19%)
		LRR_8	729..788	CDD:290566	27/110 (25%)
		leucine-rich repeat	731..754	CDD:275380	12/49 (24%)
		LRR_8	855..933	CDD:290566	27/85 (32%)
		leucine-rich repeat	855..901	CDD:275380	12/52 (23%)
		leucine-rich repeat	902..924	CDD:275380	10/22 (45%)
		leucine-rich repeat	925..949	CDD:275380	9/23 (39%)
		P-loop_NTPase	993..1211	CDD:304359	9/44 (20%)
		COR	1230..1471	CDD:292713
		STYKc	1796..2092	CDD:214568
		STKc_LRRK	1801..2095	CDD:270902
AT2G25790	NP_180150.1	PLN00113	12..960	CDD:215061	149/652 (23%)
		leucine-rich repeat	74..98	CDD:275380
		leucine-rich repeat	99..124	CDD:275380	4/19 (21%)
		leucine-rich repeat	125..146	CDD:275380	9/55 (16%)
		leucine-rich repeat	147..170	CDD:275380	5/25 (20%)
		leucine-rich repeat	171..194	CDD:275380	7/25 (28%)
		leucine-rich repeat	195..218	CDD:275380	8/22 (36%)
		leucine-rich repeat	219..242	CDD:275380	4/22 (18%)
		leucine-rich repeat	243..266	CDD:275380	10/28 (36%)
		leucine-rich repeat	267..290	CDD:275380	6/31 (19%)
		leucine-rich repeat	291..314	CDD:275380	7/34 (21%)
		leucine-rich repeat	315..336	CDD:275380	7/20 (35%)
		leucine-rich repeat	339..362	CDD:275380	2/22 (9%)
		leucine-rich repeat	363..383	CDD:275380	6/19 (32%)
		leucine-rich repeat	387..405	CDD:275380	2/17 (12%)
		leucine-rich repeat	411..434	CDD:275380	7/24 (29%)
		leucine-rich repeat	435..479	CDD:275380	7/53 (13%)
		leucine-rich repeat	480..498	CDD:275380	3/17 (18%)
		leucine-rich repeat	504..525	CDD:275380	6/20 (30%)
		leucine-rich repeat	528..551	CDD:275380	10/22 (45%)
		leucine-rich repeat	552..575	CDD:275380	9/22 (41%)
		leucine-rich repeat	576..596	CDD:275380	6/43 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1805
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050