| Sequence 1: | NP_001262770.1 | Gene: | Pi3K92E / 42446 | FlyBaseID: | FBgn0015279 | Length: | 1088 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006210.1 | Gene: | PIK3CB / 5291 | HGNCID: | 8976 | Length: | 1070 | Species: | Homo sapiens |
| Alignment Length: | 1086 | Identity: | 412/1086 - (37%) |
|---|---|---|---|
| Similarity: | 625/1086 - (57%) | Gaps: | 53/1086 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 27 PPCMRFSVNLWKNEML----NWVDLICLLPNGFLLELRVNPANTIQVIKVEMVNQAKQMPLGYVI 87
Fly 88 KEACEYQVYGIS-TFNIEPYTDETKRLSEVQPYFGILSLGERTDTTSFSSDYELTKMVNGMIGTT 151
Fly 152 FDHNRTHGSPEIDDFRLYMTQTCDNIELERSAYTWQQRLLYEHPLRLANSTKMPELIRERHPTRT 216
Fly 217 FLIVVKNENDQSTFTLSVNEQDTPFSLTESTLQKMNRSQMKMNDRTS--DYILKVSGRDEYLLGD 279
Fly 280 YPLIQFLYIQEMLSDSAVPNVVL-----------QSVYRLESYINHHNEQAMVTKRPLPKKRTVH 333
Fly 334 LHKSISSLWDMGNYFQLTLHSISNVNFDKTRALKVGVHVCLYHGDKKLCAQRSTDSPNGNFDTFL 398
Fly 399 FNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSN----NKDIALKDVPYNKNPLAWVNTT 459
Fly 460 IFDHKDILRTGRHTLYTW-TYADDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPS 523
Fly 524 EEVVLQYAADREQVNRLQRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRE 588
Fly 589 LPEELSILLHCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDE 653
Fly 654 DLLLYLLQLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVY 718
Fly 719 LKGCKHHVAPLRKQLHVLEKLKQ-GSLI---AKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLN 779
Fly 780 PSFRCSGVTPDRCKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWK 844
Fly 845 RDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPAD 909
Fly 910 KLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRERVP 974
Fly 975 FVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGLPELSSEKDL 1039
Fly 1040 DYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASHNFSKN 1085 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pi3K92E | NP_001262770.1 | PI3K_p85B | 56..132 | CDD:295322 | 20/76 (26%) |
| PI3K_rbd | 200..307 | CDD:197540 | 37/119 (31%) | ||
| C2_PI3K_class_I_beta_delta | 339..517 | CDD:176075 | 58/182 (32%) | ||
| PI3Ka_I | 552..723 | CDD:238444 | 72/170 (42%) | ||
| PI3Kc_I | 727..1084 | CDD:270709 | 186/360 (52%) | ||
| PIK3CB | NP_006210.1 | PI3K_p85B | 41..118 | CDD:197539 | 22/80 (28%) |
| PI3K_rbd | 180..288 | CDD:197540 | 36/108 (33%) | ||
| C2_PI3K_class_I_beta_delta | 324..501 | CDD:176075 | 58/182 (32%) | ||
| Nuclear localization signal | 410..418 | 3/7 (43%) | |||
| PI3Ka_I | 532..702 | CDD:238444 | 72/173 (42%) | ||
| PI3Kc_IA_beta | 706..1067 | CDD:270717 | 186/362 (51%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165146184 | |
| Domainoid | 1 | 1.000 | 276 | 1.000 | Domainoid score | I1749 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 734 | 1.000 | Inparanoid score | I605 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG57536 | |
| OrthoDB | 1 | 1.010 | - | - | D204282at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001201 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42149 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100986 | |
| Panther | 1 | 1.100 | - | - | O | PTHR10048 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X531 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.870 | |||||