DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5466 and eya-1

DIOPT Version :9

Sequence 1:	NP_650901.2	Gene:	CG5466 / 42444	FlyBaseID:	FBgn0038815	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_001021055.1	Gene:	eya-1 / 173293	WormBaseID:	WBGene00001377	Length:	503	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	59/308 - (19%)
Similarity:	100/308 - (32%)	Gaps:	81/308 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 PGGSAAGSTSSVASSSSSANVEIDLSKS-TGAK-VPQVPVPPQLQHLTKQQQSTLQTQLSQISAA 293
            |.|:   |..|:|::|.|:.:...|..| .|.| :|.|    .|..:::...||..|.....|..
Worm    27 PTGN---SNFSMATTSDSSTIWTALPASQPGDKDIPTV----DLAAISEAYGSTSSTTSLTSSVT 84

  Fly   294 AAHHQQQQQQQQQQQQQQQQQQQQAAAKHQQQLTAAL---------------------IQQQNRV 337
            :       |.|.....|.........|.:.||:||.|                     :...:..
Worm    85 S-------QYQYNSYPQYAMYTSANPANYYQQVTANLRAGTTAFPYSLTTPSYYGSYPVDYTSAA 142

  Fly   338 LAQQNLEKLSNHLSPLEKQRVFAQLDPKHFDPMAVAAAAANLQIQGLMQSQAVAAAVAANQQTPA 402
            .|.||         |...........| :::|:....|||         ..:||::|........
Worm   143 AAYQN---------PYYTNLRGGTAAP-YYNPLNATTAAA---------YASVASSVLGTDAVNL 188

  Fly   403 ATTTSAAGGAAAGPQAHHGHHPLPPPSQSPHSSSSSS-------------------SHSSLDQIT 448
            .|::..:.|..:...:.......|..|:...:.|.|.                   |.:.|..:|
Worm   189 GTSSDGSTGVPSTVTSFSLKEKKPKVSKKKKTGSCSPGDETYARVFIWDIDDIAVISRNYLASVT 253

  Fly   449 HKNVADSLRSNLDSIESNKDLLALHNGA----WATGDANRMDHLAVGQ 492
            |.|...:..:|  |:....:.:||:|.|    :..||...::...|.:
Worm   254 HTNEFYARAAN--SVSHLMERIALNNFADVNEFLEGDITNIEDAVVDE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5466	NP_650901.2	DUF3736	100..221	CDD:289317
eya-1	NP_001021055.1	HAD_Eya	230..503	CDD:319789	14/72 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1980
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950