Protein Alignment Pus1 and PUS3

DIOPT Version :9

• Sequence 1: NP_001163664.1
• Gene: Pus1 / 42440
• FlyBaseID: FBgn0038811
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_112597.4
• Gene: PUS3 / 83480
• HGNCID: 25461
• Length: 481
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 113/445 - (25%)
• Similarity: 170/445 - (38%)
• Gaps: 114/445 - (25%)

  Fly    38 DKLEVEKEARKEAKELEGEAVKDANRIKRTLKRKKWVDWKEQDEKDAANGVKRAPFDPADRIKRK 102
            |:.:.|| ..|..:|||    ::..|:|:...:.| .|...::....|...||| ||.:.. .|:
Human     7 DRNQTEK-LLKRVRELE----QEVQRLKKEQAKNK-EDSNIRENSAGAGKTKRA-FDFSAH-GRR 63

  Fly   103 KSAILLSYCGANYYGM--QRNPGMQTIEEELFKAMLKHKWITEDSFEQIQISCFQRAARTDKGVS 165
            ..|:.::|.|..|.|.  |.|.. .||||:||:|:.|.:.:     |..|.|.:.|..|||||||
Human    64 HVALRIAYMGWGYQGFASQENTN-NTIEEKLFEALTKTRLV-----ESRQTSNYHRCGRTDKGVS 122

  Fly   166 AARQVCSVKL----PEELDLEAFNAD-------------------LPQQIRLFGVERVTKGFNAK 207
            |..||.|:.|    |...|.|.||..                   ||..||:.....|...|:|:
Human   123 AFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSAR 187

  Fly   208 DQCNARTYTYTLP-------TVAFAPFEEKVDDVHDTFRISPELLQKVKETLKLYEGTKNFHNFT 265
            ..|..|||.|..|       |:.:|                   .||       |.||.:|.|..
Human   188 FSCLERTYRYFFPRADLDIVTMDYA-------------------AQK-------YVGTHDFRNLC 226

  Fly   266 SKKSFLDPSS-----KRFIMSFTSSEPFRSP------QDIEFVTLKVKGQSFMLHQIRKMVGLAI 319
            .    :|.::     :|.|:|.......:||      :..:....:|.||:|:.||:|.|:.:..
Human   227 K----MDVANGVINFQRTILSAQVQLVGQSPGEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILF 287

  Fly   320 AIVRGNTTAATLERALTEE----RLDLPMAPGLGLVLDTVHYERYNDRYGKDGIHNPLTWQAQEA 380
            .|.:|......::..|..|    :....||....|||....:|.....|.:         :|||.
Human   288 LIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENVKWIYDQ---------EAQEF 343

  Fly   381 QVQEFIEREIFSQIYKTEAEQRNMLDWIGTLHYHSYDTRTEDAPPPSSEDKKVKG 435
            .:..      ..|::...|.:.:||        :|.....:..|.|.....|:.|
Human   344 NITH------LQQLWANHAVKTHML--------YSMLQGLDTVPVPCGIGPKMDG 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pus1	NP_001163664.1	TruA	102..362	CDD:223179	82/306 (27%)
		PseudoU_synth_PUS1_PUS2	106..357	CDD:211335	80/297 (27%)
PUS3	NP_112597.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..50		4/21 (19%)
		PseudoU_synth_ScPus3	67..329	CDD:211336	80/297 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810