DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pus1 and PUSL1

DIOPT Version :9

Sequence 1:	NP_001163664.1	Gene:	Pus1 / 42440	FlyBaseID:	FBgn0038811	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_024308825.1	Gene:	PUSL1 / 126789	HGNCID:	26914	Length:	394	Species:	Homo sapiens

Alignment Length:	143	Identity:	39/143 - (27%)
Similarity:	59/143 - (41%)	Gaps:	27/143 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PADRIKRKKSAILLSYCGANYYGM------QRNPGMQTIEEELFKAMLKHKWITEDSFEQIQISC 153
            ||....|.:..:...|.|.::.|:      ||..|:|...||..:.:        :|.|.::
Human     5 PASGSVRARYLVYFQYVGTDFNGVAAVRGTQRAVGVQNYLEEAAERL--------NSVEPVR--- 58

  Fly   154 FQRAARTDKGVSAARQVCSVKL---------PEELDLEAFNADLPQ-QIRLFGVERVTKGFNAKD 208
            |..::|||.||.|......:.:         |.|:..||.|..|.. .||:....||...|:|:.
Human    59 FTISSRTDAGVHALSNAAHLDVQRRSGRPPFPPEVLAEALNTHLRHPAIRVLRAFRVPSDFHARH 123

  Fly   209 QCNARTYTYTLPT 221
            ...:|||.|.|.|
Human   124 AATSRTYLYRLAT 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pus1	NP_001163664.1	TruA	102..362	CDD:223179	36/136 (26%)
Pus1	NP_001163664.1	PseudoU_synth_PUS1_PUS2	106..357	CDD:211335	36/132 (27%)
PUSL1	XP_024308825.1	PseudoU_synth	18..>158	CDD:320773	36/130 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810