Protein Alignment Srp72 and srp72

DIOPT Version :10

• Sequence 1: NP_650898.1
• Gene: Srp72 / 42439
• FlyBaseID: FBgn0038810
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001116259.1
• Gene: srp72 / 496794
• XenbaseID: XB-GENE-994739
• Length: 674
• Species: Xenopus tropicalis
• Alignment Length: 683
• Identity: 283/683 - (41%)
• Similarity: 405/683 - (59%)
• Gaps: 46/683 - (6%)

  Fly     1 MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDDPTALHCKVVCLVQLSKFEEA 65
            |:.......|.:...:.:|||.|.|.:|.:|:|::|:||.||.||.||||||||||:|...|:||
 Frog     1 MANAGGGASAPLATLWGEVNKAGQNGDFTRALKSLNKILQVAKDDVTALHCKVVCLIQNGNFKEA 65

  Fly    66 YKFIEKN--RLSS--LFFEKAYCEYQLNKQQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDE 126
            ...|..|  .|:|  :.||||||||:||:.:.|||||:  |.......||||..|||||||||.:
 Frog    66 LNVIHSNIKVLTSDVIAFEKAYCEYRLNRIETALKTIE--GASQKSEKLKELHGQVLYRLERYSD 128

  Fly   127 CLDSYRDIIKNTSDEYEEERRTNLSAVAANLAVDQTKEVPE---VPEDTYEQYFNSACIQANRQK 188
            ||..|||||:|:.|:|:|||:||||||.|.:::.: |:.||   :.|.|||..:||||....:..
 Frog   129 CLSVYRDIIRNSQDDYDEERKTNLSAVLAAMSIWE-KKTPEDFGIQESTYELCYNSACTLIGQGH 192

  Fly   189 YAEAERKLRTSEKLC----LEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLRHK 249
            ..:...|||.:|:||    .||...:||:|..|:.:|..|:||::||||||.:|..:|...::.|
 Frog   193 LRKGMTKLREAEELCRQSISEDADLTEEDIEAELAIIHGQMAYIMQLQGKTDDALQLYNQIIKLK 257

  Fly   250 PKDAALVAVASNNLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNAGD 314
            |.|..|:||.:||::.|||||||||||||::...|:..|.:|..:|.|.|..|..||::|||..|
 Frog   258 PTDVGLMAVVANNIITVNKDQNVFDSKKKVKLTNAEGVEHKLCKKQLQAIEFNKALLSMYTNQAD 322

  Fly   315 QVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLL 379
            |.:::|..|....|: ....:||:..||.::::|.:|:|.||:||..|..:....|..:.||:|.
 Frog   323 QCRKISASLQSQDPE-HLLPVLIQAAQLCREKQHAKAVEMLQEFADQHPDNAAQIKLTMAQLKLA 386

  Fly   380 QGNRKDAIETLLSLGEAKYKPGVVSALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMW 444
            |||...|...|.|:.|.:..||:|||||:::...::..:|..:..:|:.||::|:..|.....:.
 Frog   387 QGNVTKACMILKSIKELEQTPGMVSALVTMHSYDEDIDSAIEVFSNAISWYQENQPISPLHLSLV 451

  Fly   445 RQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTA 509
            |:||.|.|:.|..:.|.|.||:|.|.||.|...||||:.||:....::|..||:.||..:|:...
 Frog   452 REAANFKLKHGRKKDAISDLEQLWKQNPKDIHTLAQLISAYSLVDAEKAKILSKHLPSSDTMKLK 516

  Fly   510 SEIDALE---AANWVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPER 571
            .::||||   .|.::  .|.|.|.|..:.:....|.::|||  .:|:||||||||:.:|.|||||
 Frog   517 VDVDALENSTGATFI--RKKAAKVAGEQAKEQGQTDIKKKK--KKKKKGKLPKNYDPKVTPDPER 577

  Fly   572 WLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSPAT-PVYQETAPG--- 632
            |||..||:.:|.|:.|.:...:.||:||..|.||.:.|.|.    |.:||.| |.....|||
 Frog   578 WLPMRERSYYRGKKKGKKKDQIGKGTQGATSAAAAELDASK----TASSPPTSPRPGLVAPGGSS 638

  Fly   633 --------PRQQ--------HRKGGHKKKKGGR 649
                    ||.|        .:|...||||||:
 Frog   639 SSSSNVIPPRHQKPVGAAGTKKKQQQKKKKGGK 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp72	NP_650898.1	Spy	36..>347	CDD:443119	151/321 (47%)
		TPR repeat	45..71	CDD:276809	16/25 (64%)
		SRP_TPR_like	52..155	CDD:435703	61/106 (58%)
		TPR repeat	75..101	CDD:276809	16/27 (59%)
		LapB	<321..515	CDD:442196	66/193 (34%)
		SRP72	534..579	CDD:462494	23/44 (52%)
srp72	NP_001116259.1	PEP_TPR_lipo	<24..482	CDD:274350	201/461 (44%)
		TPR repeat	45..75	CDD:276809	17/29 (59%)
		TPR repeat	80..103	CDD:276809	14/22 (64%)
		TPR repeat	184..212	CDD:276809	8/27 (30%)
		TPR repeat	217..256	CDD:276809	16/38 (42%)
		TPR repeat	343..368	CDD:276808	11/24 (46%)
		TPR repeat	373..401	CDD:276808	10/27 (37%)
		SRP72	533..585	CDD:462494	27/53 (51%)