Protein Alignment Srp72 and srp72

DIOPT Version :10

• Sequence 1: NP_650898.1
• Gene: Srp72 / 42439
• FlyBaseID: FBgn0038810
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: XP_073778534.1
• Gene: srp72 / 327335
• ZFINID: ZDB-GENE-030131-5546
• Length: 670
• Species: Danio rerio
• Alignment Length: 681
• Identity: 274/681 - (40%)
• Similarity: 395/681 - (58%)
• Gaps: 46/681 - (6%)

  Fly     1 MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDDPTALHCKVVCLVQLSKFEEA 65
            |:..:.|    :.|.:.::|:.|.|.:|.:|:||||:||....||.|||.||:|||:|...|:||
Zfish     1 MASGSGP----VAALWTEINRCGQNGDFTRALKAVNKILHENKDDVTALRCKIVCLIQNGGFKEA 61

  Fly    66 YKFIE---KNRLSSLF-FEKAYCEYQLNKQQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDE 126
            ...|.   |:..|.:. ||||||||:||:.:.|||||.  |:......||||..|||||||||||
Zfish    62 LNVINTHTKSLTSDMIGFEKAYCEYRLNRVENALKTIQ--GIPEQTDKLKELYGQVLYRLERYDE 124

  Fly   127 CLDSYRDIIKNTSDEYEEERRTNLSAVAANLAVDQTKE--VPE---VPEDTYEQYFNSACIQANR 186
            ||..|:|:|:|:.|||||||:||||||   ||...|.|  .||   :||.:||..:|:||....:
Zfish   125 CLAVYKDLIRNSQDEYEEERKTNLSAV---LAAQSTWENTPPEDLGLPESSYELCYNAACCLIGQ 186

  Fly   187 QKYAEAERKLRTSEKLC----LEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLR 247
            .:..:|.:||:.:|:||    .||...:||:|..|:.||..|:|||:||||:|::|..:|:..::
Zfish   187 GELGQAMKKLQKAEELCRKSLAEDSDMTEEDIDAELAVIHSQMAYVIQLQGRTEDALQLYSQVIK 251

  Fly   248 HKPKDAALVAVASNNLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNA 312
            .||.|..|:||.:||::.:||||||||||||::...|:..|.:|..:|.|.|.:|..|||:|||.
Zfish   252 LKPSDVGLLAVTANNIITINKDQNVFDSKKKVKLTNAEGVEHKLAKKQLQAIEINKALLAMYTNQ 316

  Fly   313 GDQVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQ 377
            .||..:|...| ||........:||:..||.::::|.:|||.||:|:..|.......|..:.||.
Zfish   317 ADQCNKLLSSL-QTQNPTHPRPVLIQVAQLCREKQHSKAIELLQRFSDQHPESASGIKLTMAQLY 380

  Fly   378 LLQGNRKDAIETLLSLGEAKYKPGVVSALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSD 442
            |.||:...|.:.|.|:.|.|||||::|||:::|...::..:|..:...|:.:|:..:..|.....
Zfish   381 LTQGHVTKACDILKSIEEFKYKPGMISALITMYTHEEDIDSAIDVFSQAIQYYQSEQPGSSIHLS 445

  Fly   443 MWRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLT 507
            :.|:||.:.|:.|..:.|.|.||:|.|.|.||...||||:.||:.....:|..||:.||..:.:.
Zfish   446 LVREAANYKLKYGRKKEATSDLEQLWKQNTNDIHTLAQLISAYSLVDQDKAKALSKHLPSPDKMA 510

  Fly   508 TASEIDALE---AANWVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDP 569
            ...::|.||   .|.::.. ||||....:  :|....| |..|.:.:|:||||||||:...:|||
Zfish   511 FNVDVDELENSHGATYIRK-KAAKVVGES--QPKEQGP-EDVKKKKKKKKGKLPKNYDPNSSPDP 571

  Fly   570 ERWLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSP------------- 621
            |||||..||:.:|.|:.|.:.:.|.:|:||..|||..:.|.|........||
Zfish   572 ERWLPMRERSYYRGKKKGKKKEQVGRGTQGTTSGATAELDASKTATSPPTSPRPGSGTGAPSSSG 636

  Fly   622 ---ATPVYQETAPGPRQQHRKGGHKKKKGGR 649
               |.|..|:....|....:|...||||||:
Zfish   637 SSTAIPPRQQKPAAPAAARKKAPPKKKKGGK 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp72	NP_650898.1	Spy	36..>347	CDD:443119	151/323 (47%)
		TPR repeat	45..71	CDD:276809	14/28 (50%)
		SRP_TPR_like	52..155	CDD:435703	61/106 (58%)
		TPR repeat	75..101	CDD:276809	16/26 (62%)
		LapB	<321..515	CDD:442196	64/193 (33%)
		SRP72	534..579	CDD:462494	22/44 (50%)
srp72	XP_073778534.1	None