Protein Alignment Srp72 and srp72

DIOPT Version :10

• Sequence 1: NP_650898.1
• Gene: Srp72 / 42439
• FlyBaseID: FBgn0038810
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_587719.1
• Gene: srp72 / 2538791
• PomBaseID: SPCC320.10
• Length: 561
• Species: Schizosaccharomyces pombe
• Alignment Length: 598
• Identity: 149/598 - (24%)
• Similarity: 260/598 - (43%)
• Gaps: 65/598 - (10%)

  Fly    24 NNQEFDKAVKAVNRI-LGVAPDDPTALHCKVVCLVQLSKFEEAYKFIEKN-RLSSLFFEKAYCEY 86
            :.:|.::..:.:.:| :|   |..:.::.||:.|:.:.::|.|.|.|||. ..:...:|:|||.:
pombe     4 HEEEIEELAQRIGKIEVG---DTKSDIYQKVLNLIDIERYEHALKIIEKYLGETDAVYERAYCAF 65

  Fly    87 QLNKQQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDECLDSYRDIIKNTSDEYEEERRTNLS 151
            ||.|:..:|:  |...||       .|:.|..|||..:.:.|..| :.::|...|...:.|.|:.
pombe    66 QLGKEDFSLE--DKQFLQ-------HLQAQKAYRLSDFSKALKIY-EHLENDLPEQRADIRVNML 120

  Fly   152 AVAANLAVDQTKEVPEVPEDTYEQYFNSACIQANRQKYAEAERKLRTS-EKLCLEDECASEEEII 215
            |.|:.|...|....  |..|..:..||.|........:.:|...|.:| ||  ||:..::.|:..
pombe   121 AAASQLPGLQLNNA--VSLDDQDSVFNLATRYLTIGDWNQAIELLSSSLEK--LENSDSNSEDHK 181

  Fly   216 EEVDVIRVQLAYVLQLQG----KTKEASSIYADCLRHKPKDAALVAVASNNLVVVNKDQNVFDSK 276
            .::::.|:||.:.....|    .:||:..|..|||     |....|:..|||:.::.| |.:.|.
pombe   182 SQINLCRLQLFFAYLQAGDNEKASKESLKISKDCL-----DETSQAIFVNNLISMSID-NPYISF 240

  Fly   277 KKIRAA-LADACESRLTSRQKQVIALNNCLLALYTNAGDQVQQLSQKLAQTYPQVEFEALLIR-- 338
            :.:... |..|..|.|.|::||.|. |..||.:  ..|.|.....:|.......:.|..:|:|
pombe   241 RDLHGTNLEKALSSLLASQKKQFIR-NLALLDM--AVGKQRSVRKEKKRNPEESIYFSTILLREE 302

  Fly   339 CTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLLQGNRKDA------IETLLSLGEA- 396
            ...|...:|....:|.|.|    ..|...|....::|.::..||.:.|      :.|.|...::
pombe   303 TKSLISPKKLPGYLENLFK----SDSDNIVVALLLMQHKISNGNFRGALSIYQKLRTSLEASQSL 363

  Fly   397 --KYKPGVVSALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMWRQ-AAEFHLRGGAS- 457
              .|.||:|....:|:....:....|.||..|.::::|.:.....|....|. .|....|...|
pombe   364 SVLYSPGLVGLGDALHYKIQSTGFKSQLLHEAANYWRKQQSCEAKLLLCTRSLLAHLDERAPVST 428

  Fly   458 -ETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAANWV 521
             :...|.:::||:.....:::::..|.|......:....:.:.|...:.|.|..::|.:|.....
pombe   429 IQDDMSVIDDLLQWKGPISELVSCKVAALCYLDKEIESGMDKYLVPTKDLITGIDVDDIEIRGVP 493

  Fly   522 MSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPERWLPKYERTGFRKKRG 586
            :||.......:.:...|.|:      .:.|||:...||::|.:..|||:||:||.:||..:.|..
pombe   494 VSAAIGPIKRSVEANSSNSS------KKTRKRRKPTPKSFNPKATPDPQRWIPKRDRTNVKIKSK 552

  Fly   587 GARGKDVIKGSQG 599
            |       |..||
pombe   553 G-------KSMQG 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp72	NP_650898.1	Spy	36..>347	CDD:443119	87/320 (27%)
		TPR repeat	45..71	CDD:276809	7/25 (28%)
		SRP_TPR_like	52..155	CDD:435703	32/103 (31%)
		TPR repeat	75..101	CDD:276809	9/25 (36%)
		LapB	<321..515	CDD:442196	41/207 (20%)
		SRP72	534..579	CDD:462494	15/44 (34%)
srp72	NP_587719.1	SRP_TPR_like	30..125	CDD:435703	33/104 (32%)
		PEP_TPR_lipo	<34..>353	CDD:274350	92/345 (27%)
		SRP72	<513..545	CDD:462494	13/37 (35%)