Protein Alignment Septin2 and Septin7

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001107212.1
• Gene: Septin7 / 64551
• RGDID: 620469
• Length: 437
• Species: Rattus norvegicus
• Alignment Length: 428
• Identity: 174/428 - (40%)
• Similarity: 277/428 - (64%)
• Gaps: 22/428 - (5%)

  Fly     9 DKKEVHLRTL-----KQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSF 68
            :::.|:..|:     ...|:|||.:||:|:..|||:.||.|.:|.:||:|||||||:::||.|..
  Rat    11 EERSVNCSTMVAQPKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDL 75

  Fly    69 EST----PSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFEN 129
            .|.    ||.....:|:::.....::|..|:|.|||.||.|:||.::..:.::.|:||||::||:
  Rat    76 YSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFED 140

  Fly   130 YLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVE 194
            ||..|.::.|..:.  |:|:..|||||.|:|||||.||:..||:|..||||||:||||||::..|
  Rat   141 YLNAESRVNRRQMP--DNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEE 203

  Fly   195 LQRFKAKIIQELNANGVHIYQFP-TDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYP 258
            .|:||.:|::|:..:.:.||:|| ||||...:....:...:|.|||||...|:|..|.:|.||||
  Rat   204 CQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYP 268

  Fly   259 WGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSD-NK----- 317
            ||..:|||..||||..||.|||||:|:|:::.|:..|||.||.::|..:.::.||:: ||
  Rat   269 WGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTK 333

  Fly   318 -PISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKR 381
             |::   ..|.:|..|:|:::..|.|:.|:|..:||||..:||:||.:|..:.|::|::...:.:
  Rat   334 SPLA---QMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHK 395

  Fly   382 KLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSKKK 419
            :|||.|:..||:..:::.:::.|...:.:.||.|:|||
  Rat   396 ELEEKRRQFEEEKANWEAQQRILEQQNSSRTLEKNKKK 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	125/272 (46%)
		PTZ00121	<285..393	CDD:173412	37/114 (32%)
Septin7	NP_001107212.1	CDC_Septin	47..317	CDD:206649	125/271 (46%)
		Interaction with SEPTIN12. /evidence=ECO:0000250|UniProtKB:Q16181	47..317		125/271 (46%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	57..64		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	113..116		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	194..197		2/2 (100%)
		PRK12704	337..>433	CDD:237177	30/98 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..437		16/56 (29%)