Protein Alignment Septin2 and SEPTIN10

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001308427.1
• Gene: SEPTIN10 / 151011
• HGNCID: 14349
• Length: 544
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 278/417 - (66%)
• Similarity: 339/417 - (81%)
• Gaps: 8/417 - (1%)

  Fly    11 KEVHLRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPSPH 75
            |..::|:|..||||||:||||||||:|:|.||.||::|:||||:|||||:||||||:||...|.|
Human    34 KRENIRSLTMSGHVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTNFEDYESSH 98

  Fly    76 TLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRS 140
            ..|:|||||.|||||||||:|||||.:|||:||||||::|::.:|||||||||.|||||||||||
Human    99 FCPNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKIKRS 163

  Fly   141 LVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQE 205
            |.|.||||||:|||||.||||.||:|||:.||.||||||||||||||||:||.|||:||.|::.|
Human   164 LFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQKFKIKLMSE 228

  Fly   206 LNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHC 270
            |.:|||.||||||||:|:|:.|.:||..:|||||||.:.:|||||:::|||||||.||||||.||
Human   229 LVSNGVQIYQFPTDDDTIAKVNAAMNGQLPFAVVGSMDEVKVGNKMVKARQYPWGVVQVENENHC 293

  Fly   271 DFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAE 335
            ||||||||||.|||||:||:||||||||||:.:||:|||:||..:|||:|.|:|:||||.....|
Human   294 DFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVGPENKPVSVQETYEAKRHEFHGE 358

  Fly   336 LQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRR 400
            .|.||||::||||||||||||.|||:|::|.||||.|||.|.||:.||||.|:.|||:.:.|.::
Human   359 RQRKEEEMKQMFVQRVKEKEAILKEAERELQAKFEHLKRLHQEERMKLEEKRRLLEEEIIAFSKK 423

  Fly   401 K--------QQLATAHHTLTLGKSKKK 419
            |        |........|...|.:||
Human   424 KATSEIFHSQSFLATGSNLRKDKDRKK 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	196/267 (73%)
		PTZ00121	<285..393	CDD:173412	71/107 (66%)
SEPTIN10	NP_001308427.1	CDC_Septin	63..331	CDD:206649	196/267 (73%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	73..80		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	125..128		1/2 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	208..211		2/2 (100%)