Protein Alignment Septin2 and Septin10

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001365992.1
• Gene: Septin10 / 103080
• MGIID: 1918110
• Length: 456
• Species: Mus musculus
• Alignment Length: 414
• Identity: 264/414 - (63%)
• Similarity: 331/414 - (79%)
• Gaps: 8/414 - (1%)

  Fly    14 HLRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPSPHTLP 78
            |.|:|...|||||:|||||||::|::.||.||::|:||||:|||||::|||||:||...|.|..|
Mouse    14 HPRSLSMCGHVGFESLPDQLVDRSIEQGFCFNILCVGETGIGKSTLINTLFNTNFEELESSHFCP 78

  Fly    79 SVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVT 143
            .|:|:|.|||||||||||||||.:|||:||||||:||::.:|||||.|||.||||||||||:|..
Mouse    79 CVRLRAQTYELQESNVRLKLTIVNTVGFGDQINKEDSYQPIVDYIDDQFEAYLQEELKIKRALFN 143

  Fly   144 CHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNA 208
            .||||||:|||||.||||.|::|||:.||.||:||||||:|||||||||.|||:||.|::.||..
Mouse   144 YHDSRIHVCLYFIAPTGHSLRTLDLLTMKSLDNKVNIIPLIAKADTISKSELQKFKMKLMNELVI 208

  Fly   209 NGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFV 273
            |||.||||||||:|.::.|.:||.|:|||||||.:.||||||:::.||||||.||||||.|||||
Mouse   209 NGVQIYQFPTDDDTTSKINGAMNGHLPFAVVGSMDEIKVGNKMVKGRQYPWGIVQVENENHCDFV 273

  Fly   274 KLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQS 338
            |||||||.|||||:||:||.|||||||:.:|::|||.|:..:|||:|.|:|:||||.....|.|.
Mouse   274 KLREMLICTNMEDLREQTHMRHYELYRRCKLQEMGFVDMGPENKPLSLQETYEAKRHEFYGERQR 338

  Fly   339 KEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRK-- 401
            |||:::||||||||||||.|||:|::|.||||.|||.|.||:.||||.|:.|||:.:.|.::|
Mouse   339 KEEQMKQMFVQRVKEKEAILKEAERELQAKFEHLKRIHQEERMKLEEKRRMLEEESVAFAKKKAT 403

  Fly   402 ------QQLATAHHTLTLGKSKKK 419
                  |....:..::...|.:||
Mouse   404 CELFPNQSFLASGSSIRKDKDRKK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	188/267 (70%)
		PTZ00121	<285..393	CDD:173412	67/107 (63%)
Septin10	NP_001365992.1	CDC_Septin	40..308	CDD:206649	188/267 (70%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	50..57		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	102..105		1/2 (50%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	185..188		2/2 (100%)
		PTZ00121	<274..426	CDD:173412	82/151 (54%)