DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5412 and C25G4.2

DIOPT Version :9

Sequence 1:	NP_650895.1	Gene:	CG5412 / 42434	FlyBaseID:	FBgn0038806	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_502376.1	Gene:	C25G4.2 / 178194	WormBaseID:	WBGene00007730	Length:	221	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	86/222 - (38%)
Similarity:	119/222 - (53%)	Gaps:	14/222 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KVRVLCLHGYRQNGEAFKNKLGSFRKFANKYAEFVFITAPHVAKALESAAEPVPEQRSWW-ANKD 93
            |:|:||||||||..::|:.|.||.||.....|||.|:...|..    :..|.|...|:|| :|.:
Worm     6 KLRILCLHGYRQCDQSFRQKTGSTRKLVKSLAEFEFVNGVHSV----AVDEHVDSSRAWWFSNNE 66

  Fly    94 DGSFKGTNKGGPAFGFQESLRCVEEAWRTQGPFQGLLGFSQGACFVGLICG---LAKKKLTSIRP 155
            ..||........|.||:||:..|.:.....|||.|||||||||..|.|:..   |.:.||..||
Worm    67 AMSFSSRESTEVAVGFEESVAAVVKFIEENGPFDGLLGFSQGASMVHLLIAKAQLGEIKLPGIR- 130

  Fly   156 EFAVLASGFLSGSLVHMSAYEEAI-SIPTLHIYGQTDEIIPKEMSESLAARFKNAEVLE--HSGG 217
             ||:..|||||.|..|.|.....| ..|::|::|..|||:.:..||.:|..| :.|.|.  |.||
Worm   131 -FAIFFSGFLSLSSKHDSLTLLRIKEFPSMHVFGDADEIVARPKSEKMADMF-DVEPLRIAHDGG 193

  Fly   218 HYFPATAQQKQTFINFFQDRLQEYLEH 244
            |..|:.::.|:....|.:::|...:|:
Worm   194 HVVPSMSKHKEKIAGFMREQLDRKIEN 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5412	NP_650895.1	FSH1	28..230	CDD:281892	83/206 (40%)
CG5412	NP_650895.1	MhpC	<177..244	CDD:223669	21/69 (30%)
C25G4.2	NP_502376.1	FSH1	1..206	CDD:281892	83/206 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161927
Domainoid	1	1.000	131	1.000	Domainoid score	I3225
eggNOG	1	0.900	-	-		E1_KOG2551
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6086
Inparanoid	1	1.050	138	1.000	Inparanoid score	I3110
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53056
OrthoDB	1	1.010	-	-		D1190789at2759
OrthoFinder	1	1.000	-	-		FOG0002782
OrthoInspector	1	1.000	-	-		oto20534
orthoMCL	1	0.900	-	-		OOG6_102370
Panther	1	1.100	-	-	LDO	PTHR48070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R361
SonicParanoid	1	1.000	-	-		X2182
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840