Protein Alignment TFAM and TOX

DIOPT Version :10

• Sequence 1: NP_732527.1
• Gene: TFAM / 42433
• FlyBaseID: FBgn0038805
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_055544.1
• Gene: TOX / 9760
• HGNCID: 18988
• Length: 526
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 32/139 - (23%)
• Similarity: 64/139 - (46%)
• Gaps: 15/139 - (10%)

  Fly    34 DPSRANDTDHRPLTPPRPLAAASISNTPAVPSKTLEEQLGLPPRPKKPLTPYFRFMREQRPKLKA 98
            |.|:.|..:.||        |:.:...|..|.|..::.   |..|:||::.|..|.|:.:..:|.
Human   228 DTSKINGGEKRP--------ASDMGKKPKTPKKKKKKD---PNEPQKPVSAYALFFRDTQAAIKG 281

  Fly    99 ANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEERTKYDATLTEEQRAEIKQLK-- 161
            .||..|..||.:.::..|.....:.|:..:.:.:..::.|:::...|.|:|..:..:|...:|
Human   282 QNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTS 346

  Fly   162 --QDLVDAK 168
              ..|:::|
Human   347 QPPQLINSK 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMG-box_SF	78..138	CDD:469606	14/59 (24%)
		HMG-box_SF	168..263	CDD:469606	1/1 (100%)
TOX	NP_055544.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..178
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..264		11/46 (24%)
		Nuclear localization signal. /evidence=ECO:0000255	237..256		6/26 (23%)
		HMG-box_TOX-like	262..331	CDD:438811	15/68 (22%)