DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and 3xHMG-box2

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_194111.1	Gene:	3xHMG-box2 / 828480	AraportID:	AT4G23800	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	203	Identity:	53/203 - (26%)
Similarity:	95/203 - (46%)	Gaps:	30/203 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 PPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYV 139
            |.:||.|::.:..:..|:|..|:..|..:  |||.:...:.|.:...:.|...:...|::::.|:
plant   252 PLKPKHPVSAFLVYANERRAALREENKSV--VEVAKITGEEWKNLSDKKKAPYEKVAKKNKETYL 314

  Fly   140 EERTKYDATLTEE---QRAEIKQL----------------KQDLVDAKERRQLRKRVKEL--GRP 183
            :...:|..|..||   |:.|.::|                |.|.:..||:...:|:.:.:  .:|
plant   315 QAMEEYKRTKEEEALSQKKEEEELLKLHKQEALQMLKKKEKTDNLIKKEKATKKKKNENVDPNKP 379

  Fly   184 KKPASAFLRFIASERINTPQGDKQTYREWHQKTTA----KWTRLSDSEKEVYMQESRKEMELYRK 244
            |||||::..|...||....:....|.   :...||    ||..||:.||:||..::.|.||.|:|
plant   380 KKPASSYFLFSKDERKKLTEERPGTN---NATVTALISLKWKELSEEEKQVYNGKAAKLMEAYKK 441

  Fly   245 AISVWEEK 252
            .:..:.:|
plant   442 EVEAYNKK 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	14/63 (22%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	25/67 (37%)
3xHMG-box2	NP_194111.1	PTZ00121	<2..454	CDD:173412	53/203 (26%)
		HMGB-UBF_HMG-box	139..203	CDD:238686
		HMG-box	255..320	CDD:381793	14/66 (21%)
		HMGB-UBF_HMG-box	379..444	CDD:238686	25/67 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820