DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and 3xHMG-box1

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_192846.1	Gene:	3xHMG-box1 / 826709	AraportID:	AT4G11080	Length:	446	Species:	Arabidopsis thaliana

Alignment Length:	208	Identity:	53/208 - (25%)
Similarity:	96/208 - (46%)	Gaps:	40/208 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 PPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYV 139
            |.:||:|::.|..:..|:|..||..|..:  :||.:...:.|.:...:.|.......|::::||:
plant   243 PLKPKQPISAYLIYANERRAALKGENKSV--IEVAKMAGEEWKNLSEEKKAPYDQMAKKNKEIYL 305

  Fly   140 EE-----RTKYDATLTEEQRAE--IKQLKQD---LVDAKERR-QLRKRVKEL------------G 181
            :|     |||.:..:::::..|  :|..||:   |:..||:. .:.|:.||.            .
plant   306 QEMEGYKRTKEEEAMSQKKEEEEFMKLHKQEALQLLKKKEKTDNIIKKTKETAKNKKKNENVDPN 370

  Fly   182 RPKKPASAFLRFIASERINTPQGDKQTYREW----HQKTTA----KWTRLSDSEKEVYMQESRKE 238
            :||||.|::..|....|       |....|.    :...||    ||..|.:.||:||..::.:.
plant   371 KPKKPTSSYFLFCKDAR-------KSVLEEHPGINNSTVTAHISLKWMELGEEEKQVYNSKAAEL 428

  Fly   239 MELYRKAISVWEE 251
            ||.|:|.:..:.:
plant   429 MEAYKKEVEEYNK 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	17/68 (25%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	22/71 (31%)
3xHMG-box1	NP_192846.1	HMGB-UBF_HMG-box	130..193	CDD:238686
		HMGB-UBF_HMG-box	246..309	CDD:238686	17/64 (27%)
		HMGB-UBF_HMG-box	372..437	CDD:238686	22/71 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820