DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and tox4a

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_001921001.2	Gene:	tox4a / 559853	ZFINID:	ZDB-GENE-070912-576	Length:	685	Species:	Danio rerio

Alignment Length:	166	Identity:	36/166 - (21%)
Similarity:	71/166 - (42%)	Gaps:	18/166 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TTLMSSRGGLIGSLINKVRQ--VVAKDWPPSDPSRANDTDHRPLTPPRPLAAASISNTPAVPSKT 67
            :|..|..|.|....:...||  ::...:..|:||.|.      ::.|.|:..........||..|
Zfish   221 STTPSPSGSLQDEDMEDFRQKTMLVDSFAVSEPSPAQ------ISVPPPVVRRVGGKPSMVPVAT 279

  Fly    68 LE--EQLGL--------PPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQ 122
            ::  ..||:        |..|:||::.|..|.|:.:..:|..||..|..||.:.::..|.....:
Zfish   280 VDTGASLGVKKGKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEE 344

  Fly   123 LKERLQAEFKRDQQIYVEERTKYDATLTEEQRAEIK 158
            .|:..:.:.:..::.|::....|.|:...:..:|::
Zfish   345 QKQVYKRKTEAAKKDYLKALAAYRASQLSKSSSELE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	15/63 (24%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686
tox4a	XP_001921001.2	PHA03369	<215..510	CDD:223061	36/166 (22%)
tox4a	XP_001921001.2	HMG-box	300..365	CDD:238037	15/64 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900