DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and tox3

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_005169075.1	Gene:	tox3 / 555286	ZFINID:	ZDB-GENE-090312-209	Length:	587	Species:	Danio rerio

Alignment Length:	148	Identity:	37/148 - (25%)
Similarity:	67/148 - (45%)	Gaps:	15/148 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 AKDWPPSDPSRANDTD----HRPLTPPRPLAAASISNTPAVPSKTLEEQLGLPPRPKKPLTPYFR 87
            :|...||..|..|:.|    :|.:...||  |......|..|.|..::.   |..|:||::.|..
Zfish   214 SKSATPSPSSSINEDDQEEGNRVIGEKRP--APDAGKKPKTPKKKKKKD---PNEPQKPVSAYAL 273

  Fly    88 FMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEERTKYDATLTEE 152
            |.|:.:..:|..||..|..||.:.::..|.....:.|:..:::.:..::.|::....|.|:|..:
Zfish   274 FFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKSKTEAAKKEYLKALAAYRASLVSK 338

  Fly   153 QRAE------IKQLKQDL 164
            ..||      |:.::|.|
Zfish   339 AAAESAEAQTIRSVQQTL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	15/63 (24%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686
tox3	XP_005169075.1	HMG-box	264..329	CDD:238037	15/64 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900