DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and Ubtfl1

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001028965.1	Gene:	Ubtfl1 / 546118	MGIID:	3588290	Length:	394	Species:	Mus musculus

Alignment Length:	209	Identity:	48/209 - (22%)
Similarity:	106/209 - (50%)	Gaps:	25/209 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SKTLEEQLGLPPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQA 129
            :|.|.|.   |.|||:|||.|.||.:|||.|.....|:.:..::.:.|::.:....|::|:|...
Mouse    91 NKILTEH---PDRPKRPLTAYLRFYKEQRAKYCQMYPKYSNAQLTKILAEKYRQLPAEIKQRYIM 152

  Fly   130 EFKRDQQIYVEERTKY-------------------DATLTEEQRAEIKQLKQDLVDAKERRQLRK 175
            :||::::.:.::..::                   ...:..:.:.:||.:| .||..:..|.:..
Mouse   153 DFKKEKEDFQKKMRQFKKRHPVSGHPKKSVVPQSHPTKVPTKSQGDIKNVK-SLVKTESPRTVSS 216

  Fly   176 RVKELGRPKK-PASAFLRFIASERINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEM 239
            .:|..|.|:| |.:|:.:| ..|..::|:....::|:...:.:.:|.::.::|||.|..:.::..
Mouse   217 DMKFQGEPRKPPMNAYHKF-HQESWSSPELRHLSFRKRWVEISRRWHQVPENEKEHYSNQVKRLQ 280

  Fly   240 ELYRKAISVWEEKM 253
            :.||..:.:|.:::
Mouse   281 KQYRVKLDLWLKRL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	19/63 (30%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	15/64 (23%)
Ubtfl1	NP_001028965.1	HMGB-UBF_HMG-box	101..166	CDD:238686	19/64 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..197		0/29 (0%)
		HMGB-UBF_HMG-box	226..288	CDD:238686	14/62 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810