DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TFAM and RGD1563668

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_038943758.1	Gene:	RGD1563668 / 497907	RGDID:	1563668	Length:	211	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	46/214 - (21%)
Similarity:	80/214 - (37%)	Gaps:	41/214 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 GLPPRPKKPLTPYFRFMREQRPKLKAANP--QITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQ 135
            |.|.:.:..::.|..|::..|.:.|..:|  .:...|..::.|:.|....|:.|.:.:...|.|:
  Rat     4 GDPKKLRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADK 68

  Fly   136 QIYVEERTKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRF------- 193
            ..|..|...|                     ...:.:.:|:.|:...||.|.|||..|
  Rat    69 ARYEREMKTY---------------------ISPKGETKKKFKDPNAPKTPPSAFFLFCSEYRPK 112

  Fly   194 IASERINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGH 258
            |..|......||..      :|....||..:..:|:.|.:.:.|..|.|.|.|:.:..|    |.
  Rat   113 IKGEHPGLSIGDVV------KKLGEMWTNTAADDKQPYEKMAAKLKEKYEKDIAAYRAK----GK 167

  Fly   259 IDVVRHGNLIDPPEPKPRK 277
            .|..:.| ::...:.|.:|
  Rat   168 PDAAKKG-VVKAEKSKKKK 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	13/65 (20%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	20/70 (29%)
RGD1563668	XP_038943758.1	HMG_box_2	6..78	CDD:401091	15/71 (21%)
RGD1563668	XP_038943758.1	HMG_box	95..162	CDD:395407	21/72 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010