Protein Alignment TFAM and HMGB3

DIOPT Version :9

• Sequence 1: NP_732527.1
• Gene: TFAM / 42433
• FlyBaseID: FBgn0038805
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001288160.1
• Gene: HMGB3 / 3149
• HGNCID: 5004
• Length: 220
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 53/220 - (24%)
• Similarity: 87/220 - (39%)
• Gaps: 48/220 - (21%)

  Fly    73 GLPPRPKKPLTPYFRFMREQRPKLKAANPQITT--VEVVRQLSKNWSDADAQLKERLQAEFKRDQ 135
            |.|.:||..::.|..|::..|.:.|..||::..  .|..::.|:.|.....:.|.:.....|.|
Human    24 GDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKAD- 87

  Fly   136 QIYVEERTKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRF------- 193
                  :.:||           :::| |...||.    .|:.|:...||:|.|.|..|
Human    88 ------KVRYD-----------REMK-DYGPAKG----GKKKKDPNAPKRPPSGFFLFCSEFRPK 130

  Fly   194 IASERINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGH 258
            |.|.......||..      :|....|..|:||||:.|:.::.|..|.|.|.::.::.|    |.
Human   131 IKSTNPGISIGDVA------KKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSK----GK 185

  Fly   259 IDVVRHGNLIDPPEPKPRKTLASKD 283
            .|..:      .|....||.:..:|
Human   186 FDGAK------GPAKVARKKVEEED 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	14/65 (22%)
		HMGB-UBF_HMG-box	183..247	CDD:238686	22/70 (31%)
HMGB3	NP_001288160.1	HMG_box_2	33..98	CDD:370242	15/83 (18%)
		HMG_box	113..180	CDD:366139	22/72 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920