DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TFAM and Hmgxb4

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001100882.1	Gene:	Hmgxb4 / 307667	RGDID:	1305783	Length:	598	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	49/237 - (20%)
Similarity:	98/237 - (41%)	Gaps:	58/237 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 QRPKLKAANPQITTVEVVRQLSKNWS------------DADAQLKER---LQAEFKRDQQIYVEE 141
            |.|:..:||..||.::.:...|::.|            |:..::|::   .:::.|:|:..:.|:
  Rat   273 QLPEPHSANLDITGLDPILVESESSSAGELEAGELVIDDSYREIKKKKKSKKSKKKKDKDRHKEK 337

  Fly   142 ---RTKYDAT----------LTEEQRAEIKQLKQDLV------DAKERRQLRKRVKELG-RPKKP 186
               |||..:|          |.....:.|..|....:      :.|::::.:.|.:|.| :|||.
  Rat   338 RHSRTKRSSTREHGTAREHMLVSSPASSIPTLPLPALHTDGHGEKKKKKEEKDRERERGEKPKKK 402

  Fly   187 -ASAFLRFIASERI----NTPQGDKQTYREWHQKTTAKWTRLSDSEKEV------YMQESRKEME 240
             .||:..|....|:    :.|..|   :.|..:|....|.:|.:.:|.:      |:|..:.:.|
  Rat   403 NMSAYQVFCKEYRVTIVADHPGID---FGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAE 464

  Fly   241 ---LYRKAISVWEEKMIRLGHIDVVRHGNLIDPPEPKPRKTL 279
               :.|||.|......:|...:      .::.|.:..|..|:
  Rat   465 ATTVKRKASSAEGTMKVRASSV------GILSPQKKSPPTTM 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	13/67 (19%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	20/77 (26%)
Hmgxb4	NP_001100882.1	DUF4171	107..225	CDD:290491
Hmgxb4	NP_001100882.1	HMG-box	400..463	CDD:238037	15/65 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010