DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TFAM and HBP1

DIOPT Version :9

Sequence 1:NP_732527.1 Gene:TFAM / 42433 FlyBaseID:FBgn0038805 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_001231191.1 Gene:HBP1 / 26959 HGNCID:23200 Length:524 Species:Homo sapiens


Alignment Length:89 Identity:17/89 - (19%)
Similarity:32/89 - (35%) Gaps:28/89 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   184 KKPASAFLRFIASERINTPQ--------------GDKQTYREWHQKTTAKWTRLSDSEKEVYMQE 234
            |:|.:||:.|....|:...|              ||             :|.::.:.|:.:|..|
Human   445 KRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGD-------------RWKKMKNEERRMYTLE 496

  Fly   235 SRKEMELYRKA-ISVWEEKMIRLG 257
            ::...|..::. ...|:.|....|
Human   497 AKALAEEQKRLNPDCWKRKRTNSG 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TFAMNP_732527.1 HMGB-UBF_HMG-box 78..142 CDD:238686
HMGB-UBF_HMG-box 183..247 CDD:238686 14/77 (18%)
HBP1NP_001231191.1 AXH 224..350 CDD:197779
SOX-TCF_HMG-box 443..514 CDD:238684 15/81 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1641977at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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