DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and Tfam

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_033386.1	Gene:	Tfam / 21780	MGIID:	107810	Length:	243	Species:	Mus musculus

Alignment Length:	197	Identity:	61/197 - (30%)
Similarity:	103/197 - (52%)	Gaps:	25/197 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEER 142
            ||||::.|.||..||.||.||.:|.....|:||:::..|.:.....|:..:|:||.:.:.|.|..
Mouse    49 PKKPMSSYLRFSTEQLPKFKAKHPDAKLSELVRKIAALWRELPEAEKKVYEADFKAEWKAYKEAV 113

  Fly   143 TKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKR--VKE-----LGRPKKPASAFLRFIASE--- 197
            :||...||..|...:::      :|::|| |:|:  ||.     ||:||:|.||:..:::..
Mouse   114 SKYKEQLTPSQLMGMEK------EARQRR-LKKKALVKRRELILLGKPKRPRSAYNIYVSESFQE 171

  Fly   198 -RINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGHIDV 261
             :.::.||..:...|       .|..||..||:.|:|.::.:...|...:..|||:|..:|..|:
Mouse   172 AKDDSAQGKLKLVNE-------AWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWEEQMAEVGRSDL 229

  Fly   262 VR 263
            :|
Mouse   230 IR 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	24/63 (38%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	16/67 (24%)
Tfam	NP_033386.1	HMG_box	49..116	CDD:278906	24/66 (36%)
Tfam	NP_033386.1	HMGB-UBF_HMG-box	154..215	CDD:238686	16/67 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31139
Inparanoid	1	1.050	96	1.000	Inparanoid score	I5039
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49431
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	1	1.000	-	-		FOG0007031
OrthoInspector	1	1.000	-	-		oto92499
orthoMCL	1	0.900	-	-		OOG6_107571
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R14311
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870