Protein Alignment TFAM and HMG20B

DIOPT Version :9

• Sequence 1: NP_732527.1
• Gene: TFAM / 42433
• FlyBaseID: FBgn0038805
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_006330.2
• Gene: HMG20B / 10362
• HGNCID: 5002
• Length: 317
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 47/215 - (21%)
• Similarity: 87/215 - (40%)
• Gaps: 61/215 - (28%)

  Fly    74 LPPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIY 138
            ||..||.|:|.|.||:.|:|.:::..:|.:...|:.:.|...||......|:|...|.:|::|.|
Human    66 LPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAEREKQQY 130

  Fly   139 VEERTKYDAT-----LTEE-QRAEIKQ------------------------------LKQDLVDA 167
            ::|...|..:     .||: |..:||:                              ..::.:|
Human   131 MKELRAYQQSEAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDGFSTFDVPIFTEEFLD- 194

  Fly   168 KERRQLRKRVKELGRPKKPASAFLRFIASERINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYM 232
                |.:.|..||.|.:|...||            :......:...|..::...||   |:|:.:
Human   195 ----QNKAREAELRRLRKMNVAF------------EEQNAVLQRHTQSMSSARERL---EQELAL 240

  Fly   233 QESR-----KEMELYRKAIS 247
            :|.|     ::::..|:|::
Human   241 EERRTLALQQQLQAVRQALT 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	20/63 (32%)
		HMGB-UBF_HMG-box	183..247	CDD:238686	12/68 (18%)
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		2/4 (50%)
		HMGB-UBF_HMG-box	70..135	CDD:238686	21/64 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900