DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and tfam

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_002937148.2	Gene:	tfam / 100135718	XenbaseID:	XB-GENE-978256	Length:	281	Species:	Xenopus tropicalis

Alignment Length:	187	Identity:	57/187 - (30%)
Similarity:	93/187 - (49%)	Gaps:	5/187 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEER 142
            ||:|||.|.|:..||||||....|:...:::.:.::..|....:..|||.:.....:|:.|.||.
Frog    55 PKRPLTAYLRYSIEQRPKLHKQYPEAKMMDLTKIIALEWKGLPSAEKERYEVVANAEQKKYREEV 119

  Fly   143 TKYDATLTEEQ-RAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRFIASERINTPQGDK 206
            .:|...|:..| ....:|.:|.|...|..|: ::.:..|||||:|.|.|..|: ||.....:|..
Frog   120 KQYREKLSPMQLELHREQRRQRLAKRKSVRK-KRELTVLGRPKRPRSPFNIFM-SEHFQDAKGAS 182

  Fly   207 QTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGHIDVVR 263
            ...:  .:.....|.||..|:|:.|.|.:..:...|...:..|||:|:.:|..|::|
Frog   183 SQSK--MKSLRDDWERLHTSQKQTYNQLAEDDKIRYENEMKSWEEQMMEIGRGDLIR 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	21/63 (33%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	17/63 (27%)
tfam	XP_002937148.2	HMGB-UBF_HMG-box	55..120	CDD:238686	22/64 (34%)
tfam	XP_002937148.2	HMGB-UBF_HMG-box	160..221	CDD:238686	17/63 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H31139
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	1	1.000	-	-		FOG0007031
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110