DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TFAM and bbx

DIOPT Version :9

Sequence 1:	NP_732527.1	Gene:	TFAM / 42433	FlyBaseID:	FBgn0038805	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_009303743.1	Gene:	bbx / 100005540	-ID:	-	Length:	899	Species:	Danio rerio

Alignment Length:	321	Identity:	63/321 - (19%)
Similarity:	117/321 - (36%)	Gaps:	83/321 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IGSLINKVRQVVAKDWPPSDPSRANDTDHRPLTPPRPLAAASISNTPAVPSKTLEEQLGLPPRPK 79
            :.|:...:..||...|      .:.:|..:...||...::.:...:|:|..||       .|:||
Zfish   436 LDSVTFTIEAVVKGAW------GSEETPKKKPRPPESESSLTAEQSPSVKKKT-------KPKPK 487

  Fly    80 KPLTPYFRFMREQRPKL-KAAN-PQITTVEVVRQ----LSKNWSDADAQLK-------ERLQAEF 131
            |.|......|:|:.... |.|| ||  .||::.:    ..|...:.:..:|       |....:|
Zfish   488 KQLKLKDDAMQEEEEDADKVANKPQ--DVEMITEEAPMTPKTECEDEFDVKVEPPCGMEDAMLQF 550

  Fly   132 KRDQQIYVEERTKYDA-TLTEEQRAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRFIA 195
            ...:...|:|:...|| .|...|..:..::||::..:::..:..|            .|..:.:.
Zfish   551 SPMEPTEVDEKEDSDAKPLESRQEDKDPEVKQEVCGSRKSERSCK------------GALYKTLV 603

  Fly   196 SE------RINTPQGDKQTYR--------EWHQK---------TTAKWTRLSDSEKEVYMQESRK 237
            ||      |.|..:|.:.:.|        .|:.:         :..|..:.|.|:.|......:.
Zfish   604 SEGMLTSLRANVDRGKRGSMRGSVSDHEGSWNDENWGFSQAATSNPKKLKKSKSKDETTPGLGKL 668

  Fly   238 EMELYRKAISV-------WEEKMIRLGHIDVVRHGNLIDPPEP---------KPRKTLASK 282
            |.|..:|..|:       :::|.:.   :...:..:...||||         ..:|||..|
Zfish   669 EEEFEKKFNSLPQYSPLTFDKKSVA---VTKKKKNSTSSPPEPPKTCKGSSSSQKKTLFHK 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TFAM	NP_732527.1	HMGB-UBF_HMG-box	78..142	CDD:238686	18/76 (24%)
TFAM	NP_732527.1	HMGB-UBF_HMG-box	183..247	CDD:238686	15/86 (17%)
bbx	XP_009303743.1	SOX-TCF_HMG-box	83..154	CDD:238684
bbx	XP_009303743.1	DUF2028	199..344	CDD:312980
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010