Protein Alignment CG10877 and AMACR

DIOPT Version :10

• Sequence 1: NP_650894.1
• Gene: CG10877 / 42432
• FlyBaseID: FBgn0038804
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001161067.1
• Gene: AMACR / 23600
• HGNCID: 451
• Length: 394
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 117/410 - (28%)
• Similarity: 200/410 - (48%)
• Gaps: 55/410 - (13%)

  Fly    49 LHGIRILDLSRIIAGPYCTMVLADLGAEVIKVERPHFGDEARKWGPPFLKNSNDAAYFLAPNRNK 113
            |.||.:::||.:..||:|.|||||.||.|::|:||....:..:.|                 |.|
Human     3 LQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLG-----------------RGK 50

  Fly   114 RSICIDIK--RGTQLLHRLAEISDVLVENYVPGTLERYGLGYEQLRKVNPKLIYCSMTGYGSVGP 176
            ||:.:|:|  ||..:|.||.:.||||:|.:..|.:|:..||.|.|::.||:|||..::|:|..|.
Human    51 RSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGS 115

  Fly   177 YAKRPGYDVIASSVGGLMHITGER-DGPPSKVGVAVTDMSTGLYAHGAILAALYQRTRTQRGQKI 240
            :.:..|:|:...::.|::...|.. :.|.:.:.:.......||.....|:.||:.||||.:||.|
Human   116 FCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVI 180

  Fly   241 EVDLLSTCCSLLLNVGSNYLNSGV---------EAGRMGTAHSSIVP-YQSFKTKDG-YLTLGTG 294
            :.:::.         |:.||:|.:         ||.|.........| |.:::|.|| ::.:| .
Human   181 DANMVE---------GTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVG-A 235

  Fly   295 SDVQFVDLCRR---LKVEHLAQNPKFKTNKDRVTNRVELLGILEQMLSEDTSRNWMKLFEGASFP 356
            .:.||.:|..:   ||.:.|       .|:..:.:..|:......:.:|.|...|.::|:|....
Human   236 IEPQFYELLIKGLGLKSDEL-------PNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDAC 293

  Fly   357 VGPVNSIPEVFEDEHIKAIGLVKSLRHPKDETVKVVGPPVTFSEARNDARTAPPILGQHTDEVLG 421
            |.||.:..||...:|.|..|   |....:::.|.....|:..:.....:....|.:|:||:|:|.
Human   294 VTPVLTFEEVVHHDHNKERG---SFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILE 355

  Fly   422 ELLGYGPDELAKLKKDNIIQ 441
            | .|:..:|:.:|..|.||:
Human   356 E-FGFSREEIYQLNSDKIIE 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10877	NP_650894.1	CaiB	48..440	CDD:441409	115/407 (28%)
AMACR	NP_001161067.1	CaiB	1..373	CDD:441409	115/407 (28%)