Protein Alignment CG5191 and AMD2

DIOPT Version :9

• Sequence 1: NP_650893.2
• Gene: CG5191 / 42431
• FlyBaseID: FBgn0038803
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_010528.3
• Gene: AMD2 / 851829
• SGDID: S000002650
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 540
• Identity: 120/540 - (22%)
• Similarity: 197/540 - (36%)
• Gaps: 162/540 - (30%)

  Fly    71 LAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREID-NVIAMGINSVESMEE 134
            |.:.:..:::...|:..|:..|...::.::|.:.:..|.|||..|...| |..|:
Yeast    66 LRQALEAKELSCHEITAAFCHRAALIHQVVNCLSEIMFSEALRLADYYDSNRPAI---------- 120

  Fly   135 LTPLLGIPVTVKESIAVKGMTNQAG---RVFKTPQIAKSDAPVVEQIKRSGGIILLVSNTPELCL 196
            |.||.|||:::|:...|:|:....|   |.|| |:....::.:|..::..|.||.:.:..|...:
Yeast   121 LPPLYGIPISLKDQCNVEGVDTSLGYLCRTFK-PKTKNEESLIVSFLRDLGAIIFVKTTVPSSMM 184

  Fly   197 LWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWGHKPT 261
            ..:|.:|..|.|.|..:|..:.|||||||.:|:.:..|||||.:|||||.|:|:.:.|::|.|||
Yeast   185 ATDTQSNTFGYTYNSINLSFSSGGSSGGEGSLIGAHGSLLGLGTDIGGSIRIPSSYQGLFGLKPT 249

  Fly   262 ----PYA---VSFKGHHPTSDFPKWGDFFTIAPMTRYAKDLPLLLKCMSDPTGPKLTLDRPISVN 319
                ||.   .||:|......        .|.|:.|...||...:.|:.:...|.:.     .|.
Yeast   250 FGRVPYLRVDNSFEGRETIPS--------VIGPLARDLSDLRYFMSCVINICQPWVQ-----DVK 301

  Fly   320 GIRFFFMDNDGP------------SGMMRPLSRDLHAAINRVATDFNAKRVNIRKMKWSLDISLS 372
            .|.:.|..:...            .|::.|...|:.|.  :...|...|...::.:||.....||
Yeast   302 CIPYHFDSSTSKLHDNYVVGIWYGDGVIDPPPSDIRAL--KTCEDLVNKTKGMKAVKWEPSSELS 364

  Fly   373 AML--------------TMKNIETIYHK----------TEEGEQPKTV------------CKETV 401
            ..|              .:||...|..:          .|.|..|.||            .::.:
Yeast   365 RELFDLANEADVADSGNEIKNEFEISGEPLLDILKPMVLENGRPPYTVNEWWDLTKRVYNAQQLM 429

  Fly   402 K-YFFGCSDSILPSVIFGHLQNFMKIIPNSRHKHLASIIEALKTEFKEMLGNDGVFLYPTFPNTA 465
            : |:....:|..|.||... ...|...|.          :.|||..:
Yeast   430 RDYYLSFPESERPDVIISP-TTLMPFRPG----------DMLKTTLR------------------ 465

  Fly   466 HQHYQIYHKLLEPMYMAIFNTLGLPVTNCMIG---------LDRRN------------------- 502
                          |:.:||.|..|..:..:|         :|..:
Yeast   466 --------------YILLFNVLNFPSLSIPVGSVDCQIDGLMDTTSALNPEDKMIKTYWNDLIQS 516

  Fly   503 -----LPMGIQVVANPGQDH 517
                 .|:|:|||:....|:
Yeast   517 GEIDGFPIGLQVVSPTFNDN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5191	NP_650893.2	GatA	61..537	CDD:223232	120/540 (22%)
		PRK07488	63..537	CDD:236030	120/540 (22%)
AMD2	NP_010528.3	Amidase	79..539	CDD:396144	119/527 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I1462
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I1370
Isobase	1	0.950	-	0.69812	Normalized mean entropy	S4795
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46650
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	8	7.840