DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5191 and faah.2

DIOPT Version :9

Sequence 1:	NP_650893.2	Gene:	CG5191 / 42431	FlyBaseID:	FBgn0038803	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001011356.1	Gene:	faah.2 / 496823	XenbaseID:	XB-GENE-997947	Length:	582	Species:	Xenopus tropicalis

Alignment Length:	531	Identity:	130/531 - (24%)
Similarity:	222/531 - (41%)	Gaps:	97/531 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LLEIPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREIDNVIAMGIN 127
            :|.:...:||..::...:..|.|:.:|:.:...|...:|. |.|...|...:...:......|:
Frog    72 ILSLSLPELASKLKDGSLSPEMVLHSYMRKALDVTSELNC-VTDYLPECETQLVHLRGQKTKGL- 134

  Fly   128 SVESMEELTPLLGIPVTVKESIAVKGMTNQAGRVFKTPQIAKSDAPVVEQIKRSGGIILLVSNTP 192
                      |.|:|:::|::....|..:..|.:.:..:.|..|:.:.:.:|..|.:..:.:|.|
Frog   135 ----------LYGVPISLKDNFNYTGHDSTLGLLNQLNRPACEDSVIAKVLKVQGALPFMKTNIP 189

  Fly   193 ELCLLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWG 257
            :..|.::..|.:.|:|.||.:.|:|||||||||.:|:|:|.|:||:.||||||.|.|:.|.||.|
Frog   190 QSMLNYDCSNPIYGRTLNPLNHKKTPGGSSGGEGSLIAAGGSILGIGSDIGGSIRFPSAFCGICG 254

  Fly   258 HKPTPYAVSFKGHHPTSDFPKWGDFFTIAPMT-RYAKDLPLLLKCMS----------DPTGPKLT 311
            .|||...:|..|...:|...|     ::|.|. ..|:|:..|:.||.          |||.|.|.
Frog   255 FKPTANRLSKLGVKTSSAGQK-----SVAAMIGPLARDVDSLVLCMRALLCEEMFQLDPTIPPLP 314

  Fly   312 LDRPI--SVNGIRFFFMDNDGPSGMMRPLSRDLHAAINRVATDFNAKRVNIRKMKW---SLDISL 371
            .:..|  |...:|..:.:.|..:.....:.|.:|      .|....:|...:.:.:   |::.|:
Frog   315 FNEEIYSSTRPLRIGYYETDDATMATPSMKRAVH------ETKELLERAGHKMVPFTPPSVEKSM 373

  Fly   372 SAMLT---MKNIETIYHKTEEGEQPKTVCKETVK-----YFFGCSDSILPSVIFGHLQNFMKIIP 428
            ..::.   :.:..:.:....:|:|.....|..|.     |:.....|.:...:|..|...::.|.
Frog   374 FELIVKGLLADGGSTFLDNFKGDQVDPNLKTQVSTYGLPYWLKIFISFIVKPVFPRLSKLLQNIK 438

  Fly   429 NSRH-----KHLASIIEALKTEF---KEMLGNDGVFL----------YPTFPNTAHQHYQIYHKL 475
            ..|.     ||... :||.:.||   .:.|..|.|..          ||...:|| ..|.|.:.|
Frog   439 GIRSVKDLWKHHLE-VEAYRQEFISQWKKLEIDAVLCPILSPALTIGYPGKLSTA-VSYTILYNL 501

  Fly   476 LEPMYMAIFNTLGLPVTNCM----IGL--------------------DRRNLPMGIQVVANPGQD 516
            ::      |....:|||...    .||                    |...||:.:|.||.|.|:
Frog   502 VD------FPVGVVPVTTVTKDDEEGLKAYKGHKKDYWDKLLKEALTDSIGLPVSVQCVALPWQE 560

  Fly   517 HLSLAVAREME 527
            ...|.:.:|:|
Frog   561 EQCLRLMKEVE 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5191	NP_650893.2	GatA	61..537	CDD:223232	130/531 (24%)
CG5191	NP_650893.2	PRK07488	63..537	CDD:236030	130/531 (24%)
faah.2	NP_001011356.1	Amidase	94..564	CDD:366635	123/500 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950