DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5191 and SPBPB8B6.03

DIOPT Version :9

Sequence 1:	NP_650893.2	Gene:	CG5191 / 42431	FlyBaseID:	FBgn0038803	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001018764.1	Gene:	SPBPB8B6.03 / 3361182	PomBaseID:	SPBPB8B6.03	Length:	547	Species:	Schizosaccharomyces pombe

Alignment Length:	569	Identity:	132/569 - (23%)
Similarity:	225/569 - (39%)	Gaps:	134/569 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LRSAMIVFSWFVVPYSRYTNIKVIRRKLPPIRSHLLEIPAVDLAKLIRTRKIKSEEVVEAYIERC 93
            :|..|| .|.:|..| .|.|:     .|||..:.:..:..::||..|......|..|.:|:..|.
pombe    30 IRKEMI-SSGYVNTY-EYLNL-----ILPPEENAITNLSMLELATNIAKGNYTSYNVTKAFCHRA 87

  Fly    94 RQVNPLINAIVQDRFEEALEEAREIDNVIAMGINSVESMEELTPLLGIPVTVKESIAVKGMTNQA 158
            ...:.::|..::..|:|||::|:|:|:|..      ::.:.:.|..|||:::|:.:.:.|..:..
pombe    88 ALAHQILNCCIEIFFDEALKKAKELDDVFQ------KTSKVVGPFHGIPISLKDQVDLPGKDSSI 146

  Fly   159 GRVFKTPQIAKSDAPVVEQIKRSGGIILLVSNT-PELCLLWETYNNVTGQTKNPYDLKRTPGGSS 222
            |.|....: .|::..::.:|.:..|.|..|..| |...:..:|.:|:.|.|.|..::..:.||||
pombe   147 GYVSLVGK-PKTEIALLAKILQDKGAIFYVKTTVPMAMMAPQTVSNLHGYTYNALNINLSSGGSS 210

  Fly   223 GGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWGHKPTPYAVSFKGHHPTSDF------PKWGD 281
            |||.|||.||||..|:.:|||||.|:|:.|.|::..||:...:|:.  :.|:.:      |.
pombe   211 GGEGALLGSGASCCGIGTDIGGSIRIPSCFQGLYALKPSTGRISYL--NVTNSYSGQELIPS--- 270

  Fly   282 FFTIAPMTRYAKD--------------------LPLLLKCMSDPTGPKLTLDRPISVNGIRFFFM 326
              .|.||.|..||                    ||:..|..|.....||.           |..:
pombe   271 --VIGPMARSLKDIEFFTETVIASEAWKIDSKLLPIPWKNQSHLKSKKLI-----------FGVL 322

  Fly   327 DNDGPSGMMRPLSRDLHAAINRVA-----TDFNAKRVNIRKMKWSLDISLSAMLTMKNIETIYHK 386
            ..||......|:.|    |:|.|.     :.:....::|...|..||..:.........|.....
pombe   323 KTDGIVKPHPPIIR----ALNEVVAVLEKSGYEVIEISIPFQKDMLDTVVKVFSADARFEINNES 383

  Fly   387 TEEGEQPKTVCKETVKYFFGCSDSILPSVIFGHLQNFMKIIPNSRHKHLASIIEALKTEFKEMLG 451
            .:.||...:|.|..|      ||.|           |.|.|..:....|.:.:..::..|.|:..
pombe   384 QKTGEPVVSVVKRFV------SDKI-----------FKKPITVNEWWDLGNQVYKIRQMFLELWN 431

  Fly   452 NDGV----------FLYPTFPNTAHQHYQIYHKLLEPMYMAIFNTLGLPVTNCMI--------GL 498
            |..:          .:.|.:.:|:.    :.....:.:|.::||....|   |::        .:
pombe   432 NTAIQTLSGNSIDAIIAPIWASTSF----LPESKADHLYTSLFNICDCP---CVVFPFTKVDANI 489

  Fly   499 DRR------------------------NLPMGIQVVANPGQDHLSLAVA 523
            |..                        |:|:.:|||....::...||.|
pombe   490 DLSDVSYKPLNEEDKENNDMYDPVLFDNMPVCLQVVTKKLEEEKCLAAA 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5191	NP_650893.2	GatA	61..537	CDD:223232	121/537 (23%)
CG5191	NP_650893.2	PRK07488	63..537	CDD:236030	121/535 (23%)
SPBPB8B6.03	NP_001018764.1	Amidase	79..535	CDD:302749	114/508 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1324
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I1345
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9291
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	7	6.890