DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5191 and SPCC550.07

DIOPT Version :9

Sequence 1:	NP_650893.2	Gene:	CG5191 / 42431	FlyBaseID:	FBgn0038803	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_588099.1	Gene:	SPCC550.07 / 2539478	PomBaseID:	SPCC550.07	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	517	Identity:	145/517 - (28%)
Similarity:	233/517 - (45%)	Gaps:	97/517 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LPPIRSHLLE-IPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREID 119
            |.|....|.| ..|..||::|:.||:.|.|:|.|:.:|......|:|.:.:..:||||..|.|:|
pombe    47 LTPKEIELTEKYDATALAEMIKDRKVTSVELVTAFCKRAAIAQQLVNCVNELFYEEALARAAELD 111

  Fly   120 NVIAMGINSVESMEELTPLLGIPVTVKESIAVKGMTNQAGRVFKTPQIAKSDAPVVEQIKRSGGI 184
            ...|      ::...:.||.|:||:|||.|::|..|..|..:.|...||:.|:.:|..::::|.:
pombe   112 EYYA------KTGSLVGPLHGVPVSVKEHISIKNHTATASFLAKANIIAEKDSDLVATVRKAGAV 170

  Fly   185 ILLVSNTPELCLLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLP 249
            ....:..|:..:..||.:|:||.|.||::.|.|||||||||.|||...||:||:.||||||.|.|
pombe   171 FYCRTPQPQAIMHLETSSNLTGVTVNPFNRKLTPGGSSGGEGALLGIKASVLGIGSDIGGSIRSP 235

  Fly   250 AMFSGIWGHKPTPYAVSFKGHHPTSDFPKWGD---FFTIAPMTRYAKDLPLLLKCMSD------- 304
            |..:|::|.:|:...:|.||......    |.   ...:.|:.|..:|:.|.:|...|
pombe   236 AANNGLFGLRPSTLRLSRKGCQGAVS----GQETILGVVGPLGRSVRDMNLFMKACIDSQPWLDD 296

  Fly   305 ---------PTGPKLTLDRPISVNGIRFFFMDNDGPSGMMRPLSRDLHAAINRVA--TDFNAKRV 358
                     ...|..||         :...|.:|.......|::|.:..||::::  .||:...|
pombe   297 ASLLPMPWRSVAPPKTL---------KVGIMRSDNVVNPQPPVARAMQMAIDQLSKNPDFDLVDV 352

  Fly   359 NIRKMKWSLDISLSAMLTMKNIETIYHKTEEGEQPKTVCKETVKYFFGCSDSILPSVIFGHLQNF 423
            .....|:|.|: :|.|..:...:..|....:..:|                 |||      |..:
pombe   353 EPLDHKYSWDL-ISEMYWLDGGKVYYDLFNKVGEP-----------------ILP------LTEW 393

  Fly   424 MKIIPNSRHKHLASI--IEALKTEFK-------EMLGNDGVFLYPTFPNTAHQHYQIYHKLLEP- 478
            :...||.:...:.::  :.|.:.|::       :..|.| |.|.|..|:.|       .||.|.
pombe   394 IMHQPNVKPHDITAVWKLTAARDEYRNRYLKHLQAYGVD-VLLTPVGPSPA-------PKLGEAK 450

  Fly   479 --MYMAIFNTLGL-----PVTNCMIGLDRRN---LPMGIQVVAN----PGQDHLSLAVAREM 526
              .|.:::|.|.|     |||.....||.::   :||..|..||    ..:|:|...|:.::
pombe   451 YWTYTSVWNLLDLPAVVFPVTTVDPKLDVKDESYIPMNEQDAANYETYSPEDYLDAPVSLQL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5191	NP_650893.2	GatA	61..537	CDD:223232	143/512 (28%)
CG5191	NP_650893.2	PRK07488	63..537	CDD:236030	143/510 (28%)
SPCC550.07	NP_588099.1	Amidase	76..523	CDD:279733	134/488 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1324
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I1345
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9291
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	7	6.890