Protein Alignment CG5191 and FAAH2

DIOPT Version :10

• Sequence 1: NP_650893.2
• Gene: CG5191 / 42431
• FlyBaseID: FBgn0038803
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 208/556 - (37%)
• Similarity: 319/556 - (57%)
• Gaps: 47/556 - (8%)

  Fly     1 MLKSIVTVIRLHLEELWLRILGYIMRRFLRSAMIVFSWFVVPYSRYTNIKVIRRKLPPIRSHLLE 65
            |..|....|:|.|    ||.||:::....|:|:::           ...|...:...|:...||.
Human     1 MAPSFTARIQLFL----LRALGFLIGLVGRAALVL-----------GGPKFASKTPRPVTEPLLL 50

  Fly    66 IPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQDRFEEALEEAREIDNVIAMGINSVE 130
            :..:.||||||.||:|..:||:|||.|.:.|||:||.||:.|||||::||..:|..:|.......
Human    51 LSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEA 115

  Fly   131 SMEELTPLLGIPVTVKESIAVKGMTNQAGRVFKTPQIAKSDAPVVEQIKRSGGIILLVSNTPELC 195
            ::|...|.||:|:||||:..::||.|.:|.:.:...|||:||.||..:|.:|.|.|.::|..|||
Human   116 TLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC 180

  Fly   196 LLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLPAMFSGIWGHKP 260
            :.:|:.|.:.|::.|||||:...|||||||...||:..|::|:.||||||.|:||.|:||:||||
Human   181 MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKP 245

  Fly   261 TPYAVSFKGHHP----TSDFPKWGDFFTIAPMTRYAKDLPLLLKCMSDPTGPKLTLDRPISVNGI 321
            :|..|..||..|    ..:.     |....||.|||:||..:||.|:.|...:|.||..:.:..:
Human   246 SPGVVPNKGQFPLAVGAQEL-----FLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDL 305

  Fly   322 RFFFMDNDGPSGMMRPLSRDLHAAINRVATDF------NAKRVNIRKMKWSLDISLSAMLTMKNI 380
            :|::|::||.|.:|..:.:||.....:|....      :.:.|.::|||:|..:.: ||::.|.
Human   306 KFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWI-AMMSAKG- 368

  Fly   381 ETIYHKTEE--------GEQPKTVCK--ETVKYFFGCSDSILPSVIFGHLQNFMKIIPNSRHKHL 435
                |..:|        |:..|.|..  |.:|:..|.|...:||:....|:..:: ..|.:::..
Human   369 ----HDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLR-YSNEKYQKF 428

  Fly   436 ASIIEALKTEFKEMLGNDGVFLYPTFPNTAHQHYQIYHKLLEPMYMAIFNTLGLPVTNCMIGLDR 500
            .::.|:|:.|..:|||:|||||||:.|..|.:|:....:.....|..:|:.||||||.|.:||:.
Human   429 KAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNA 493

  Fly   501 RNLPMGIQVVANPGQDHLSLAVAREMERRYGGWVRP 536
            :.||:||||||.|..|||:||||:.:|:.:||||.|
Human   494 KGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5191	NP_650893.2	GatA	61..537	CDD:439924	195/496 (39%)
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	190/490 (39%)