DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DPCoAC and LEU5

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_011865.1	Gene:	LEU5 / 856391	SGDID:	S000001044	Length:	357	Species:	Saccharomyces cerevisiae

Alignment Length:	331	Identity:	122/331 - (36%)
Similarity:	176/331 - (53%)	Gaps:	47/331 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RQKIDQVVISLISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRASLRYL----QNTYANEGV 126
            |...|.:|.|.::|..:|:.|||:||||||.||.||..|.....:..||..|    ::.:.|:||
Yeast    27 RNSFDYIVRSGLAGGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGV 91

  Fly   127 LALWRGNSATMARIVPYAAIQFTAHEQWRRILHVDKDGTNTKGRRFLAGSLAGITSQSLTYPLDL 191
            ...::|:|||:.||.||||::|.|:||.|..|...|: ..:..||.::|||||:.|..:||||||
Yeast    92 RGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKE-FESHWRRLVSGSLAGLCSVFITYPLDL 155

  Fly   192 ARARMAVTDRYTGYRTLRQVFTKIWVEEGPRTL----------------FRGYWATVLGVIPYAG 240
            .|.|:|....:...: |.::..||:.|....||                :|||..||||:|||||
Yeast   156 VRVRLAYETEHKRVK-LGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYAG 219

  Fly   241 TSFFT----YETLKREY---YEVV-------------GNNKP-NTLVSLAFGAAAGAAGQTASYP 284
            .|||.    ::.||..:   |.|:             ...:| .|...|..|..||.|.|||:||
Yeast   220 VSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGMASQTAAYP 284

  Fly   285 LDIVRRRMQTMRVN--TAGGDRYPTILETLVKIYREEGVKNGFYKGLSMNWIKGPIAVGISFSTY 347
            .:|:|||:|...::  |....::.:|.|....|::|.||: ||:.|||:.:||....|..||..|
Yeast   285 FEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVR-GFFVGLSIGYIKVTPMVACSFFVY 348

  Fly   348 DLIKAW 353
            :.:| |
Yeast   349 ERMK-W 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	39/90 (43%)
		Mito_carr	169..251	CDD:278578	39/101 (39%)
		Mito_carr	279..356	CDD:278578	30/77 (39%)
LEU5	NP_011865.1	Mito_carr	32..127	CDD:395101	40/94 (43%)
LEU5	NP_011865.1	PTZ00169	38..329	CDD:240302	107/293 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I2283
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1017
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54381
OrthoFinder	1	1.000	-	-		FOG0001300
OrthoInspector	1	1.000	-	-		oto99825
orthoMCL	1	0.900	-	-		OOG6_100703
Panther	1	1.100	-	-	O	PTHR24089
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	1	1.000	-	-		X798
TreeFam	1	0.960	-	-
	12	11.860