DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DPCoAC and SLC25A23

DIOPT Version :9

Sequence 1:NP_001287430.1 Gene:DPCoAC / 42429 FlyBaseID:FBgn0067783 Length:365 Species:Drosophila melanogaster
Sequence 2:XP_011526576.1 Gene:SLC25A23 / 79085 HGNCID:19375 Length:624 Species:Homo sapiens


Alignment Length:361 Identity:126/361 - (34%)
Similarity:185/361 - (51%) Gaps:52/361 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 STGSQLSSTMTTASATLSSDLDDADTSRTQLSPSETSGV---VLVP-----ATTVTPMRQKIDQV 72
            ||..|..|..|..:....|.|......|.:.:..|...:   :.||     ...:|.|..|    
Human   174 STAEQNRSKTTVLARRSGSHLKSQHFGRPKWADHEVLDIGECLTVPDEFSKQEKLTGMWWK---- 234

  Fly    73 VISLISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRAS-------LRYLQNTYANEGVLALW 130
              .|::||.|||:::|..|||||.|:..|:        .||       |..|::.....|:.:||
Human   235 --QLVAGAVAGAVSRTGTAPLDRLKVFMQV--------HASKTNRLNILGGLRSMVLEGGIRSLW 289

  Fly   131 RGNSATMARIVPYAAIQFTAHEQWRR-------ILHVDKDGTNTKGRRFLAGSLAGITSQSLTYP 188
            |||...:.:|.|.:||:|.|:||.:|       .|||.:        ||:||||||.|:|::.||
Human   290 RGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQE--------RFVAGSLAGATAQTIIYP 346

  Fly   189 LDLARARMAVTDRYTG-YRTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKRE 252
            :::.:.|:  |.|.|| |:.|.....:|...||||..:|||...|||:|||||.....|||||..
Human   347 MEVLKTRL--TLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNW 409

  Fly   253 YYEVVGNNK--PNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGDRYPTILETLVKI 315
            :.:...::.  |..||.||.|..:...||.|||||.:||.|||. :.:..||.:. ::|..|..|
Human   410 WLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA-QASIEGGPQL-SMLGLLRHI 472

  Fly   316 YREEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLIK 351
            ..:||:: |.|:|::.|::|...||.||:..|:.:|
Human   473 LSQEGMR-GLYRGIAPNFMKVIPAVSISYVVYENMK 507

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DPCoACNP_001287430.1 Mito_carr 72..159 CDD:278578 33/100 (33%)
Mito_carr 169..251 CDD:278578 39/82 (48%)
Mito_carr 279..356 CDD:278578 29/73 (40%)
SLC25A23XP_011526576.1 EF-hand_7 16..75 CDD:290234
EFh 18..76 CDD:238008
EFh 85..142 CDD:238008
EF-hand_7 85..137 CDD:290234
Mito_carr 232..319 CDD:278578 34/100 (34%)
PTZ00169 237..510 CDD:240302 111/292 (38%)
Mito_carr 322..411 CDD:278578 43/98 (44%)
Mito_carr 420..511 CDD:278578 36/91 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1887
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.