DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and Slc25a42

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	XP_006253013.1	Gene:	Slc25a42 / 689414	RGDID:	1592346	Length:	329	Species:	Rattus norvegicus

Alignment Length:	187	Identity:	110/187 - (58%)
Similarity:	134/187 - (71%)	Gaps:	13/187 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 QVVISLISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRASLRYLQNTYANEGVLALWRGNSA 135
            ||:.||:|||.|||||||.:||||||||.||: :...||.:.:.|.|..||.|||.|:|||||||
  Rat    77 QVLSSLLSGALAGALAKTAVAPLDRTKIIFQV-SSKRFSAKEAFRLLYFTYLNEGFLSLWRGNSA 140

  Fly   136 TMARIVPYAAIQFTAHEQWRRIL-HVDKDGTNTKGR------RFLAGSLAGITSQSLTYPLDLAR 193
            ||.|::|||||||:|||:::||| |.    ...:|.      |.|||:|||.|:.||||||||.|
  Rat   141 TMVRVIPYAAIQFSAHEEYKRILGHY----YGFRGEALPPWPRLLAGALAGTTAASLTYPLDLVR 201

  Fly   194 ARMAVTDRYTGYRTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLK 250
            ||||||.:.. |..:..||.:|..|||.:||:.|:..||||||||||.||||||:||
  Rat   202 ARMAVTPKEM-YSNIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLK 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	56/87 (64%)
		Mito_carr	169..251	CDD:278578	52/88 (59%)
		Mito_carr	279..356	CDD:278578
Slc25a42	XP_006253013.1	Mito_carr	74..167	CDD:278578	58/94 (62%)
Slc25a42	XP_006253013.1	Mito_carr	<192..259	CDD:278578	43/67 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346703
Domainoid	1	1.000	112	1.000	Domainoid score	I6093
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74852
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2629
OMA	1	1.010	-	-		QHG54381
OrthoDB	1	1.010	-	-		D1253450at2759
OrthoFinder	1	1.000	-	-		FOG0001300
OrthoInspector	1	1.000	-	-		oto97565
orthoMCL	1	0.900	-	-		OOG6_100703
Panther	1	1.100	-	-	LDO	PTHR24089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X798
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770