DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DPCoAC and Slc25a19

DIOPT Version :9

Sequence 1:NP_001287430.1 Gene:DPCoAC / 42429 FlyBaseID:FBgn0067783 Length:365 Species:Drosophila melanogaster
Sequence 2:NP_001239313.1 Gene:Slc25a19 / 67283 MGIID:1914533 Length:318 Species:Mus musculus


Alignment Length:291 Identity:85/291 - (29%)
Similarity:148/291 - (50%) Gaps:23/291 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 ISGAAAGALAKTVIAPLDRTKINFQIRND--VPFS--------FRASLRYLQNTYANEGVLALWR 131
            ::|:.:|.:.:.:|:|||..||.||::.:  .|..        |:|:.:.||    .||..|.|:
Mouse    20 VAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQ----EEGPRAFWK 80

  Fly   132 GNSATMARIVPYAAIQFTAHEQWRRILH-VDKDGTNTKGRRFLAGSLAGITSQSLTYPLDLARAR 195
            |:.......:.|.|:||.|.|:...:|: .:...|:.....|:.|.|:..|:....:|:|:.|.|
Mouse    81 GHVPAQILSIGYGAVQFLAFEELTELLY
QANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTR 145

  Fly   196 MAVTDRYTGYRTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREYYEVV--G 258
            :|.......|..||:....::..|||...::|...||:.:.||||..|..|.:|||.|..::  .
Mouse   146 LAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPD 210

  Fly   259 NNKPNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQT---MRVNTAGGD--RYPTILETLVKIYRE 318
            ..:...|.:|..|..:|...:|.:||||::::|:|.   ....:|.|.  .|..:|:...::.:|
Mouse   211 GKQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQE 275

  Fly   319 EGVKNGFYKGLSMNWIKGPIAVGISFSTYDL 349
            ||.: ||:||||.:.:|..::.|..|..|:|
Mouse   276 EGTR-GFFKGLSPSLMKAALSTGFMFFWYEL 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DPCoACNP_001287430.1 Mito_carr 72..159 CDD:278578 26/91 (29%)
Mito_carr 169..251 CDD:278578 25/81 (31%)
Mito_carr 279..356 CDD:278578 25/76 (33%)
Slc25a19NP_001239313.1 Solcar 1 13..106 26/89 (29%)
Mito_carr 16..108 CDD:395101 26/91 (29%)
Solcar 2 116..202 26/85 (31%)
Mito_carr 118..203 CDD:395101 27/84 (32%)
Mito_carr 212..311 CDD:395101 29/95 (31%)
Solcar 3 214..309 29/93 (31%)
Substrate recognition. /evidence=ECO:0000250 241..246 1/4 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0752
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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