DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and SLC25A19

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001119593.1	Gene:	SLC25A19 / 60386	HGNCID:	14409	Length:	320	Species:	Homo sapiens

Alignment Length:	289	Identity:	82/289 - (28%)
Similarity:	141/289 - (48%)	Gaps:	21/289 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ISGAAAGALAKTVIAPLDRTKINFQI------RNDVPFSFRASLRYLQNTYANEGVLALWRGNSA 135
            ::|:.:|.:.:.:|:|.|..||.||:      |:|....:...|:..:.....||..|.|:|:..
Human    20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVP 84

  Fly   136 TMARIVPYAAIQFTAHEQWRRILHVDKDGTNTKGR----RFLAGSLAGITSQSLTYPLDLARARM 196
            .....:.|.|:||.:.|....::|   .|:....|    .|:.|.||...:....:|:|:.|.|.
Human    85 AQILSIGYGAVQFLSFEMLTELVH---RGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRF 146

  Fly   197 AVTDRYTGYRTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREY-YEVVGNN 260
            |.......|.|||.....::..|||:..::|...|::.:.||||..|..|.:||..| :.:....
Human   147 AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEG 211

  Fly   261 KPN-TLVSLAFGAAAGAAGQTASYPLDIVRRRMQT---MRVNTAGGD--RYPTILETLVKIYREE 319
            |.| .|.:|..|:.||...:|.:||||:.::|:|.   .....|.|.  ||..:::...::.::|
Human   212 KKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKE 276

  Fly   320 GVKNGFYKGLSMNWIKGPIAVGISFSTYD 348
            |.. ||:||||.:.:|..::.|..|.:|:
Human   277 GAL-GFFKGLSPSLLKAALSTGFMFFSYE 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	22/87 (25%)
		Mito_carr	169..251	CDD:278578	26/85 (31%)
		Mito_carr	279..356	CDD:278578	23/75 (31%)
SLC25A19	NP_001119593.1	Solcar 1	13..106		22/85 (26%)
		Mito_carr	16..111	CDD:278578	23/93 (25%)
		PTZ00169	20..293	CDD:240302	79/276 (29%)
		Solcar 2	116..202		27/85 (32%)
		Mito_carr	118..203	CDD:278578	26/84 (31%)
		Solcar 3	214..309		29/92 (32%)
		Mito_carr	216..306	CDD:278578	28/90 (31%)
		Substrate recognition. /evidence=ECO:0000250	241..246		1/4 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810