DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and slc25a25b

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	XP_009299818.1	Gene:	slc25a25b / 569227	ZFINID:	ZDB-GENE-060526-340	Length:	536	Species:	Danio rerio

Alignment Length:	294	Identity:	104/294 - (35%)
Similarity:	157/294 - (53%)	Gaps:	34/294 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LISGAAAGALAKTVIAPLDRTKINFQI---RND---VPFSFRASLRYLQNTYANEGVLALWRGNS 134
            |::|..|||:::|..|||||.|:..|:   |::   :...|...:|       ..|:.:|||||.
Zfish   257 LVAGGGAGAVSRTCTAPLDRLKVLMQVHATRSNSMGIAGGFTQMIR-------EGGLRSLWRGNG 314

  Fly   135 ATMARIVPYAAIQFTAHEQWRRILHVDKDGTN--TKG--RRFLAGSLAGITSQSLTYPLDLARAR 195
            ..:.:|.|.:||:|.|:||.:|::     |:|  |.|  .|.::|||||..:||..||:::.:.|
Zfish   315 INVLKIAPESAIKFMAYEQIKRLI-----GSNQETLGILERLVSGSLAGAIAQSSIYPMEVLKTR 374

  Fly   196 MAV--TDRYTGYR-TLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREYYE-- 255
            :|:  |.:|:|.. ..:.:|.|    ||....::||...:||:|||||.....|||||..:.:
Zfish   375 LALGRTGQYSGIADCAKHIFKK----EGMTAFYKGYIPNMLGIIPYAGIDLAVYETLKNSWLQRF 435

  Fly   256 VVGNNKPNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGDRYPTILETLVKIYREEG 320
            ...:..|...|.||.|..:...||.|||||.:||.|||...  :..|....|:......|.|.||
Zfish   436 ATDSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA--SQEGSPQMTMSGLFRHIVRTEG 498

  Fly   321 VKNGFYKGLSMNWIKGPIAVGISFSTYDLIKAWL 354
            . .|.|:||:.|::|...||.||:..|:.:|..|
Zfish   499 A-IGLYRGLAPNFMKVIPAVSISYVVYENLKITL 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	31/88 (35%)
		Mito_carr	169..251	CDD:278578	33/86 (38%)
		Mito_carr	279..356	CDD:278578	30/76 (39%)
slc25a25b	XP_009299818.1	EFh	70..129	CDD:238008
		EF-hand_7	71..131	CDD:290234
		EFh	137..208	CDD:238008
		EF-hand_7	138..205	CDD:290234
		Mito_carr	253..341	CDD:278578	32/95 (34%)
		Mito_carr	343..435	CDD:278578	35/95 (37%)
		Mito_carr	441..532	CDD:278578	36/94 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940