DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DPCoAC and slc25a23b

DIOPT Version :9

Sequence 1:NP_001287430.1 Gene:DPCoAC / 42429 FlyBaseID:FBgn0067783 Length:365 Species:Drosophila melanogaster
Sequence 2:NP_001038417.1 Gene:slc25a23b / 561087 ZFINID:ZDB-GENE-040724-220 Length:481 Species:Danio rerio


Alignment Length:391 Identity:122/391 - (31%)
Similarity:190/391 - (48%) Gaps:71/391 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LEKPNIAMSIKSTGSQLSS--------------TMTTA-----------------------SATL 32
            ::.|.|.:|::|.|..:|:              |||..                       ..:|
Zfish   111 IDVPEIQLSLRSLGVNVSTEQASRILQSIDRDGTMTIDWNEWRDHFLFNPLHNMEDIAHYWKHSL 175

  Fly    33 SSDLDDADTSRTQLSPSE-TSGVVLVPATTVTPMRQKIDQVVISLISGAAAGALAKTVIAPLDRT 96
            ..|:.:..|...:.|..| .||||         .||        |::||.|||:::|..|||||.
Zfish   176 MLDIGEQLTVPDEFSEKERRSGVV---------WRQ--------LVAGAMAGAVSRTGTAPLDRL 223

  Fly    97 KINFQIRNDVPFSFRASLRYLQNTYANEGVLALWRGNSATMARIVPYAAIQFTAHEQWRRILHVD 161
            |:..|:......:..:.   ||......|:.:|||||...:.:|.|.:||:|.|:||.:.::...
Zfish   224 KVFLQVHGTSGVTLFSG---LQGMVREGGLRSLWRGNGINVLKIAPESAIKFMAYEQIKWLIRGR 285

  Fly   162 KD-GTNTKGRRFLAGSLAGITSQSLTYPLDLARARMAV--TDRYTGYR-TLRQVFTKIWVEEGPR 222
            :: ||.....||:||||||.|:|::.||:::.:.|:.:  |.:|:|.. ..:|:..|    ||.|
Zfish   286 REGGTLRVQERFIAGSLAGATAQTIIYPMEVLKTRLTLRKTGQYSGMADCAKQILRK----EGVR 346

  Fly   223 TLFRGYWATVLGVIPYAGTSFFTYETLKREYYE--VVGNNKPNTLVSLAFGAAAGAAGQTASYPL 285
            ..::||....||:|||||.....|||||..:.:  .:|:..|..||.||.|..:...||.|||||
Zfish   347 AFYKGYVPNTLGIIPYAGIDLAVYETLKNAWLQRYCMGSADPGVLVLLACGTVSSTCGQLASYPL 411

  Fly   286 DIVRRRMQTMRVNTAGGDRYPTILETLVKIYREEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLI 350
            .::|.|||...  :|.|....:::.....|...|||. |.|:|::.|::|...||.||:..|:.:
Zfish   412 ALIRTRMQAQA--SAEGAPQLSMVGQFKHIVSHEGVP-GLYRGIAPNFLKVIPAVSISYVVYEHM 473

  Fly   351 K 351
            |
Zfish   474 K 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DPCoACNP_001287430.1 Mito_carr 72..159 CDD:278578 30/86 (35%)
Mito_carr 169..251 CDD:278578 34/84 (40%)
Mito_carr 279..356 CDD:278578 27/73 (37%)
slc25a23bNP_001038417.1 EF-hand_7 33..89 CDD:290234
EFh 33..87 CDD:238008
EFh 95..156 CDD:238008 9/44 (20%)
EF-hand_7 96..151 CDD:290234 9/39 (23%)
Mito_carr 199..279 CDD:278578 33/99 (33%)
PTZ00169 204..477 CDD:240302 101/281 (36%)
Mito_carr 289..381 CDD:278578 37/95 (39%)
Mito_carr 387..478 CDD:278578 34/91 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1887
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.940

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