DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and SPBC12D12.05c

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_595952.1	Gene:	SPBC12D12.05c / 2539713	PomBaseID:	SPBC12D12.05c	Length:	426	Species:	Schizosaccharomyces pombe

Alignment Length:	297	Identity:	88/297 - (29%)
Similarity:	151/297 - (50%)	Gaps:	24/297 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ISGAAAGALAKTVIAPLDRTKINFQIRNDV------PFSFRASLRYLQNTYANEGVLALWRGNSA 135
            |||..||.:::|..|||||.|:  .:.:|.      .:.|...|...:..:...|:.:.:.||..
pombe   132 ISGGIAGIVSRTCTAPLDRLKV--MLISDTGSKPSPKYPFATLLHTTKVLWNRNGIRSFFVGNGI 194

  Fly   136 TMARIVPYAAIQFTAHEQWRRILHVDKDGTN-TKGRRFLAGSLAGITSQSLTYPLDLARARMAVT 199
            .:.:::|.::|:|..:|..:|:|.:.....| :....:|||.:||..:|...||:|..:.|:..:
pombe   195 NVLKVMPESSIKFGTYEAMKRVLGISSSSENHSPLYSYLAGGMAGSVAQMFIYPVDTLKFRIQCS 259

  Fly   200 DRYTGYRTLRQVFT---KIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREYYEVVGNNK 261
            |...|......:.:   :::...|.|..:||....:||:.||:.|...|:|.|||.:..::.:..
pombe   260 DLSRGQHGKSIILSNAKELYKSVGIRGYYRGVLVGILGMFPYSATDLGTFEGLKRTWIGILASRD 324

  Fly   262 ---------PNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGDRYPTILETLVKIYR 317
                     ||.|| :||||.:|:.|.|..:||:::|.|:|| :..:|....|...::...|..:
pombe   325 NVDPQDVKLPNGLV-MAFGALSGSTGATIVFPLNVIRTRLQT-QGTSAHPATYDGFIDCFYKTTK 387

  Fly   318 EEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLIKAWL 354
            .||.: |.|||||.|.:|...:|.||:..|:..|.||
pombe   388 NEGFR-GLYKGLSPNLLKVAPSVAISYLVYENCKKWL 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	23/87 (26%)
		Mito_carr	169..251	CDD:278578	24/84 (29%)
		Mito_carr	279..356	CDD:278578	27/76 (36%)
SPBC12D12.05c	NP_595952.1	Abhydrolase	<50..115	CDD:304388
		Mito_carr	123..218	CDD:278578	23/87 (26%)
		PTZ00169	131..423	CDD:240302	86/295 (29%)
		Mito_carr	227..320	CDD:278578	26/92 (28%)
		Mito_carr	332..424	CDD:278578	37/95 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.900