DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and F17E5.2

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_510081.3	Gene:	F17E5.2 / 181399	WormBaseID:	WBGene00008924	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	107/376 - (28%)
Similarity:	184/376 - (48%)	Gaps:	45/376 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IKSTGSQLSSTMTTASA-TLSSDLDDADTSRTQLSPSETSGVVLVPATTVTPMRQKID------- 70
            |||...::...:....| ::...:|.:.:|...|:..: ..::|.|:   |.||..:|
Worm   161 IKSYCKEMGVNLDDQKAMSIVKKMDQSGSSSVNLNEFQ-DFMLLYPS---TDMRDMVDFWRHNLI 221

  Fly    71 ---------------QVVIS------LISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRASL 114
                           |.::|      |::|..|||:::|..||.||.|:..|: |....:....:
Worm   222 IDIGEDGQVPEDFTPQELLSGVWWRHLVAGGVAGAMSRTCTAPFDRIKVYLQV-NSTKTNKLGVV 285

  Fly   115 RYLQNTYANEGVLALWRGNSATMARIVPYAAIQFTAHEQWRRILHVDKDGTNTKG-RRFLAGSLA 178
            ..:...:|..|:.:.||||...:.:|.|.:|::|..::|.:|.:...|.|..... .|.||||.|
Worm   286 SCVHLLHAEGGIKSFWRGNGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSA 350

  Fly   179 GITSQSLTYPLDLARARMAVTDRYTGY--RTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGT 241
            |..||:..||:::.:.|:|:  |.||.  :.:.....|::.:||.:..::||...:||:|||||.
Worm   351 GAISQTAIYPMEVMKTRLAL--RRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGI 413

  Fly   242 SFFTYETLK---REYYEVVGNNKPNTLVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGD 303
            ....||:||   .:||  ..:.:|..|..||.|..:...||.|||||.:||.|:|...::.....
Worm   414 DLTVYESLKSMYTKYY--TEHTEPGVLALLACGTCSSTCGQLASYPLALVRTRLQARAISPKNST 476

  Fly   304 RYPTILETLVKIYREEGVKNGFYKGLSMNWIKGPIAVGISFSTYDLIKAWL 354
            :..|::.....|.:.||. .|.|:|::.|::|...||.||:..|:.::..|
Worm   477 QPDTMVGQFKHILQTEGF-TGLYRGITPNFMKVIPAVSISYVVYEKVRKQL 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	26/92 (28%)
		Mito_carr	169..251	CDD:278578	32/87 (37%)
		Mito_carr	279..356	CDD:278578	25/76 (33%)
F17E5.2	NP_510081.3	FRQ1	67..206	CDD:227455	8/45 (18%)
		EFh	74..160	CDD:298682
		EFh	140..201	CDD:238008	7/40 (18%)
		Mito_carr	244..333	CDD:278578	25/89 (28%)
		PTZ00169	249..526	CDD:240302	90/282 (32%)
		Mito_carr	337..429	CDD:278578	32/93 (34%)
		Mito_carr	434..527	CDD:278578	31/94 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940