DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DPCoAC and slc-25A42

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_492333.1	Gene:	slc-25A42 / 172656	WormBaseID:	WBGene00009666	Length:	294	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	151/291 - (51%)
Similarity:	210/291 - (72%)	Gaps:	10/291 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 VVISLISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRASLRYLQNTYANEGVLALWRGNSAT 136
            ||:||.:||.|||||||.|||||||||.||:.:...:|||:::::::.||...|..||:||||||
Worm    14 VVLSLSAGAIAGALAKTTIAPLDRTKIYFQVSSTRGYSFRSAIKFIKLTYRENGFFALYRGNSAT 78

  Fly   137 MARIVPYAAIQFTAHEQWRRILHVDKDGTNTKGRRFLAGSLAGITSQSLTYPLDLARARMAVTDR 201
            |||:||||::||.|.||::::|.||::|:.|..:|::.||||..|:..:|||||.|:||::|:.:
Worm    79 MARVVPYASMQFAAFEQYKKLLKVDENGSRTPVKRYITGSLAATTATMITYPLDTAKARLSVSSK 143

  Fly   202 YTGYRTLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREYYEVVGNNKPNTLV 266
            .. |.:|:.||.|.:.|.|.:.|:||.:.|:||||||||:|||||||||..|.:..|..: |:..
Worm   144 LQ-YSSLKHVFVKTYKEGGIQLLYRGIYPTILGVIPYAGSSFFTYETLKIMYRDHRGEVE-NSYY 206

  Fly   267 SLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGDRYPTILETLVKIYREEGVKNGFYKGLSM 331
            .:.||..||..||::|||||||||||||.|:.:....     |..|:.||..||:|.|.||||||
Worm   207 RMLFGMLAGLIGQSSSYPLDIVRRRMQTGRIPSGWSP-----LRALIHIYHTEGLKRGLYKGLSM 266

  Fly   332 NWIKGPIAVGISFSTYDLIKAWLTELANLRR 362
            ||:|||||||:||:||:.:   |..:.:|:|
Worm   267 NWLKGPIAVGVSFTTYEKV---LELVGHLKR 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	50/86 (58%)
		Mito_carr	169..251	CDD:278578	42/81 (52%)
		Mito_carr	279..356	CDD:278578	43/76 (57%)
slc-25A42	NP_492333.1	PTZ00169	8..271	CDD:240302	137/263 (52%)
		Mito_carr	10..100	CDD:278578	50/85 (59%)
		Mito_carr	106..198	CDD:278578	46/92 (50%)
		Mito_carr	203..291	CDD:278578	49/95 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162749
Domainoid	1	1.000	108	1.000	Domainoid score	I4051
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74852
Inparanoid	1	1.050	291	1.000	Inparanoid score	I1689
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54381
OrthoDB	1	1.010	-	-		D1253450at2759
OrthoFinder	1	1.000	-	-		FOG0001300
OrthoInspector	1	1.000	-	-		oto18177
orthoMCL	1	0.900	-	-		OOG6_100703
Panther	1	1.100	-	-	LDO	PTHR24089
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	1	1.000	-	-		X798
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800