DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DPCoAC and slc25a23

DIOPT Version :9

Sequence 1:	NP_001287430.1	Gene:	DPCoAC / 42429	FlyBaseID:	FBgn0067783	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001135638.1	Gene:	slc25a23 / 100216197	XenbaseID:	XB-GENE-5998763	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	103/288 - (35%)
Similarity:	158/288 - (54%)	Gaps:	23/288 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LISGAAAGALAKTVIAPLDRTKINFQIRNDVPFSFRASLRYLQNTYANEGVLALWRGNSATMARI 140
            |::|..|||:::|..|||||.|:..|:......|.   ||.|:......||.:|||||...:.:|
Frog   189 LLAGGVAGAVSRTGTAPLDRLKVLMQVHGSQGLSI---LRGLRVMIEEGGVRSLWRGNGINVIKI 250

  Fly   141 VPYAAIQFTAHEQWRRILHVDKDGTNTKGRRFLAGSLAGITSQSLTYPLDLARARMAV--TDRYT 203
            .|.:||:|.|:||.::::....:....: .||:||||||..:|:..||:::.:.|||:  |.:|:
Frog   251 APESAIKFMAYEQIKKLIRGQHETLRVR-ERFIAGSLAGAIAQTAIYPMEVLKTRMALRRTGQYS 314

  Fly   204 GYR-TLRQVFTKIWVEEGPRTLFRGYWATVLGVIPYAGTSFFTYETLKREY---YEVVGNNKPNT 264
            |.. ..||:..    .||.|..|:||...:||::||||.....|||||..:   |....:..|..
Frog   315 GMSDCARQILR----NEGVRAFFKGYIPNLLGIVPYAGIDLAVYETLKNTWLQRYRSSTSADPGV 375

  Fly   265 LVSLAFGAAAGAAGQTASYPLDIVRRRMQTMRVNTAGGDRYPTILETLVKIYREEGVKNGF---Y 326
            ||.||.|..:...||.|||||.:||.|||. :.:..|..:.     ::|.::|....:.||   |
Frog   376 LVLLACGTVSSTCGQIASYPLALVRTRMQA-QASVQGSPQL-----SMVALFRHIVAREGFLGLY 434

  Fly   327 KGLSMNWIKGPIAVGISFSTYDLIKAWL 354
            :|::.|::|...||.||:..|:.:|..|
Frog   435 RGIAPNFMKVIPAVSISYVVYENMKRLL 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DPCoAC	NP_001287430.1	Mito_carr	72..159	CDD:278578	32/82 (39%)
		Mito_carr	169..251	CDD:278578	35/84 (42%)
		Mito_carr	279..356	CDD:278578	27/79 (34%)
slc25a23	NP_001135638.1	EF-hand_7	18..75	CDD:290234
		EFh	19..73	CDD:238008
		EFh	59..104	CDD:238008
		EFh	85..142	CDD:238008
		EF-hand_7	85..137	CDD:290234
		Mito_carr	185..270	CDD:278578	32/83 (39%)
		PTZ00169	190..462	CDD:240302	101/285 (35%)
		Mito_carr	279..366	CDD:278578	36/90 (40%)
		Mito_carr	372..463	CDD:278578	34/97 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1887
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.030