Protein Alignment Stat92E and stat1

DIOPT Version :9

• Sequence 1: NP_001262760.1
• Gene: Stat92E / 42428
• FlyBaseID: FBgn0016917
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_012826050.2
• Gene: stat1 / 780397
• XenbaseID: XB-GENE-482166
• Length: 751
• Species: Xenopus tropicalis
• Alignment Length: 798
• Identity: 210/798 - (26%)
• Similarity: 351/798 - (43%)
• Gaps: 159/798 - (19%)

  Fly     1 MSLWKRISSHVDCE--QRMAAYYEEKGMLELRLCLAPWIEDR-------------IMSEQITPNT 50
            |:.|..: ..:|.:  :::...|::...:|:|..||.|:|.:             |:...:....
 Frog     1 MAQWYEL-QQIDTKFLEQVHQLYDDSFPMEIRQYLAQWLESQDWEHAANNVSLATILFHGLLSQL 64

  Fly    51 TDQLERVALKFNEDLQQKLLSTRTASDQALKFRVVELCALIQRISAVELYTHLRSGLQKELQLVT 115
            .||..|.:|:.|..||..:..::.......:...|::..:|            .|.|::|.:::
 Frog    65 DDQYSRFSLENNFLLQHNIRKSKRNLQDHFQEDPVQMAMII------------NSCLREESKIL- 116

  Fly   116 EKSVAATAGQSMPLNPYNMNNTPMVTGYMVDPSDLLAVSNSCNPPVVQGIGPIHNVQNTGIASPA 180
                    |.:...|...:.:|.  |..|:|....|...             :.:|:|..:.
 Frog   117 --------GNARAYNKNQVGSTQ--TTVMLDKQKELDKK-------------VTDVRNRALE--- 155

  Fly   181 LGMVTPKVEL-------YEVQHQIMQSL-NEFGNCA-NALK----LLAQNYSYMLNSTSSPNAEA 232
               |...|:|       |:.:::.:||. ||....| |.||    ||:..:.::|
 Frog   156 ---VEQDVKLLEDLQDEYDFKYKTVQSRENEHNGLAQNELKKEKMLLSNMHIHVL---------- 207

  Fly   233 AYRSLIDEKAAIVLTMRRSFMYYESLHEMVIHELKNWRHQQAQAGNGAPFNEGSLDDIQRCFEML 297
            ..|..|..|.|.::::..     .:.:.::..||..|:|:|..|..|.|.| ..||.:|..|
 Frog   208 LKRKAIIHKIAELMSVTD-----HTQNALINEELVEWKHRQQIACIGGPPN-ACLDQLQSWF--- 263

  Fly   298 ESFIAHMLAAVKELMRVRLVTEEPELTH-----------LLEQVQNAQKNLVCSAFIVDKQP--- 348
             :.||..|..|::.:: :|...|.:||:           |.|:.|:..|.|:.|:|:|::||
 Frog   264 -TTIAKSLQQVRQQLK-KLEELEQKLTYDGDPITCNKQALQERTQSLFKQLLQSSFVVERQPCMP 326

  Fly   349 -----PQVMKTNTRFAASVRWLIGSQLGIHNNPPTVECIIMSEIQSQRFVTRNTQMDNSSLSGQS 408
                 |.|:||..:|...:|.|:  :|...|....|:.:...::..:..|....:.   ::.|..
 Frog   327 THPQRPLVLKTGVQFTVKLRLLV--KLQELNYQLKVKALFDKDVNDKNIVKGFRKF---NILGTH 386

  Fly   409 SGEIQNASSTMEYQQNNHVFSASFRNMQLKKIKRAEKKGTES---VMDEKFALFFYTTTTVNDFQ 470
            : ::.|    || :..|...:|.||::|||:.|.|..:..|.   |.:|...|.|.|........
 Frog   387 T-KVMN----ME-ESTNGSLAAEFRHLQLKEQKNAGSRTNEGPLIVTEELHCLSFETQLCQLGLV 445

  Fly   471 IRVWTLSLPVVVIVHGNQEPQSWATITWDNAFAEIVRDP--FMITDRVTWAQLSVALNIKFGSCT 533
            :.:.|.|||:|||.:.:|.|..||:|.|.|......::.  |:......|..||..|:.:|.|.|
 Frog   446 VDLETSSLPIVVISNVSQLPSGWASILWYNMLTSETKNVSFFLNPPAARWPLLSDVLSWQFSSVT 510

  Fly   534 GRSLTIDNLDFLYEKLQREERS---EYITWNQFCKEPMPDRSFTFWEWFFAIMKLTKDHMLGMWK 595
            .|.|..|.|..|.|||.....|   :.|.|.:||||.|.|::|.||.|...|::|.|.|:|.:|.
 Frog   511 KRGLNADQLSMLGEKLLGPTTSSGDDLIPWTRFCKENMNDKNFPFWLWIEGILELIKKHLLCLWN 575

  Fly   596 AGCIMGFINKTKAQTDLLRSVYGIGTFLLRFSD-SELGGVTIAYV---NENGLVTMLAPWTARDF 656
            .|.|:|||:|.:.:. ||:. ...||||||||: |:.|.:|..:|   ..:.|...:.|:|.|:.
 Frog   576 DGFIVGFISKERERA-LLKE-KAPGTFLLRFSESSKEGAITFTWVERPQNDPLFHSVEPYTKREL 638

  Fly   657 QVLNLADRIRDLDVLC----------WLHPSDRNASPVKRDVAFGEFYSKRQE-PEPLVLD--PV 708
            ..:...|.||:..|:.          :|:|.      ..:|.|||::||:.:| .||:.||  ..
 Frog   639 SAVTFPDIIRNYKVMAAENIPENPLRFLYPD------TPKDNAFGKYYSRPKEADEPMDLDGPKG 697

  Fly   709 TGYVKSTL----HVHVCR 722
            |||:|:.|    .||..|
 Frog   698 TGYIKTELISVSEVHPSR 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stat92E	NP_001262760.1	STAT_int	2..119	CDD:214942	22/131 (17%)
		STAT_alpha	151..340	CDD:279369	48/212 (23%)
		STAT_bind	342..587	CDD:280939	79/260 (30%)
		SH2_STAT_family	578..696	CDD:198175	42/131 (32%)
stat1	XP_012826050.2	STAT_int	2..119	CDD:214942	23/138 (17%)
		STAT1_CCD	138..313	CDD:341076	47/214 (22%)
		STAT1_DBD	317..477	CDD:341083	48/170 (28%)
		SH2	558..706	CDD:417686	52/155 (34%)
		STAT1_TAZ2bind	714..738	CDD:371931	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D166575at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11801
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020