DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stat92E and steap4.1

DIOPT Version :9

Sequence 1:	NP_001262760.1	Gene:	Stat92E / 42428	FlyBaseID:	FBgn0016917	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001015852.1	Gene:	steap4.1 / 548569	XenbaseID:	XB-GENE-5814015	Length:	458	Species:	Xenopus tropicalis

Alignment Length:	352	Identity:	67/352 - (19%)
Similarity:	120/352 - (34%)	Gaps:	106/352 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 GSQLGIHNNPPTVECIIMSEIQSQR--FVTRNTQMDNSSLSGQSSGEIQNASSTMEYQQNNHVFS 429
            |:::..|:.......||:..|..:.  |:.:.|::    |:|:...::.|.....:|.::|..:.
Frog    60 GAEVFSHSEAAQRASIIILAIHRENYDFLKQYTEV----LNGKVLVDVSNNLKINQYPESNAEYL 120

  Fly   430 A----------SFRNMQLKKIKRAEKKGTESVM---DEKFALFFYTTTTVNDFQIRVWTLSLPVV 481
            |          :|..:....::......:..|.   ||     .|...:|.|.   |.||.|
Frog   121 ARMVPEAKVVKAFNTISAWALQSGALDASRQVFVCGDE-----IYAKQSVMDI---VRTLGL--- 174

  Fly   482 VIVHGNQEPQSWATITWDNAFAEIVRDPFMITDRVTWAQLSVALNIKFGSCTGRSLTIDNLDFLY 546
                   .|....|:...|   |:...|.         ||.....|....|:|.::.|    |||
Frog   175 -------TPLDQGTLLASN---EVENYPL---------QLFPMWRIPIFICSGFTILI----FLY 216

  Fly   547 EKLQ---------REERSEYITWNQFCKEPMPDRSFTFWEWFFAIMKLTKDHMLGMWKAGCIMGF 602
            ..|.         :|:.|..|..:      :|:|.|.    ..:::.|...::.|:
Frog   217 CVLTEVLYPCVTLKEDASYLIAIS------IPNRVFP----IVSLILLALVYLPGI--------- 262

  Fly   603 INKTKAQTDLLRSVYGIGTFLLRFSD---------SELGGVTIAYVNENGLVTMLAP------WT 652
               ..|...|.|     ||...||.|         .:||.|.:||...:.:.|::.|      |.
Frog   263 ---IAAVLQLYR-----GTKYSRFPDWLDKWMLCRKQLGLVALAYAFLHAIYTLVMPIRYYVRWW 319

  Fly   653 ARDFQVLNLA--DRIRDLDVLCWLHPS 677
            :.::.:..:.  :....|:...||..|
Frog   320 SNNYIITQIKTNNTYEFLNHYAWLSDS 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stat92E	NP_001262760.1	STAT_int	2..119	CDD:214942
		STAT_alpha	151..340	CDD:279369
		STAT_bind	342..587	CDD:280939	46/243 (19%)
		SH2_STAT_family	578..696	CDD:198175	22/117 (19%)
steap4.1	NP_001015852.1	COG2085	20..200	CDD:224996	31/173 (18%)
steap4.1	NP_001015852.1	Ferric_reduct	249..392	CDD:366815	22/115 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860