Protein Alignment MFS9 and VHT1

DIOPT Version :10

• Sequence 1: NP_650889.1
• Gene: MFS9 / 42426
• FlyBaseID: FBgn0038799
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_011579.1
• Gene: VHT1 / 852956
• SGDID: S000003297
• Length: 593
• Species: Saccharomyces cerevisiae
• Alignment Length: 575
• Identity: 112/575 - (19%)
• Similarity: 201/575 - (34%)
• Gaps: 163/575 - (28%)

  Fly     5 ESPKNGKHLEQVHQNNNEITESEPLTWRFWRKQRY-IVVLLAFFGFFNVYSLRVNLSVAIVAMTE 68
            |..|:.|..|.::.|:...|::|       |:..| :.:::|.:.|...:|..|:|:....|...
Yeast    96 EYKKSRKWYEFLYPNHTTQTKAE-------RRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVS 153

  Fly    69 N-RTVFDADGNVSYQQDFPWDS--KQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGST 130
            | :...:..||     |:.:.|  ...|.|:....:.|:|.:|                   .|.
Yeast   154 NMKEDLNMKGN-----DYVYTSTIANVGAIVFQLPFMYLLPRF-------------------PSH 194

  Fly   131 AILTLLT--------PMAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAF 187
            .||.::.        ....::||......|.|...|....:|....:...|..|.|.:....:.|
Yeast   195 IILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFF 259

  Fly   188 AGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVIWYI----------TWLV--FVKAG-PE-- 237
            .|...|:|.    ||.|.::. ::|:..|.|..|..|..          |.::  ||..| |.
Yeast   260 CGQQLGSVT----SGLLQSRI-FKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKC 319

  Fly   238 LDRFCSKEEC-------------DYIQKT-IGYVGSKHVKHPWRAIFTSMPFYAIMA------SH 282
            ...|.:.||.             |.:.|: :..:.|:.:   |:.:|.:..|:.::.      ::
Yeast   320 YSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKL---WKKVFCTPAFWVLVVFDTCSWNN 381

  Fly   283 FSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAV-SGYLADWLQVKGIWTT-T 345
            .:...|.|||      :|:....:.:.:...||.:| ..:|....: ..:.||..:.|.|:.. .
Yeast   382 MTAYSGSYTL------WLKSNTKYSIAQVNNLSVIP-ACLGFAYVIFCAFGADLFRCKWIFMVFA 439

  Fly   346 QVRRNFNCGAFLAQTV------FMMLTAYLLDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQ- 403
            .:....:|...:...:      :...|.|            .:|......|| |..:.|...||
Yeast   440 AIMNTVSCALLIKWDIPSKAKWYAFFTTY------------FSVAASPCLWS-FINDFLRFDPQV 491

  Fly   404 HASVLMGI----GNTFATIPGIVSPLL------TGYVVTNQTSDEWRIIFFISAGIYLVGCVIYW 458
            .|...:.|    .:|:|.||.:..|.:      |||.|:        :||....|::..  |:.:
Yeast   492 KAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVS--------LIFGAIYGLWTF--VVLF 546

  Fly   459 FYCSGDLQEWAKTPEQK-----------AQEAEEKAQLQLTQTAGFVNSGAELKD 502
            ||         |..|:|           :.:.||..:        ||....|.:|
Yeast   547 FY---------KRNEKKHALGNGIILYDSNKGEELPE--------FVKKNMEERD 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	MFS_SLC17	43..461	CDD:340876	93/482 (19%)
VHT1	NP_011579.1	MFS_FEN2_like	124..542	CDD:340885	91/477 (19%)