Protein Alignment MFS9 and SEO1

DIOPT Version :10

• Sequence 1: NP_650889.1
• Gene: MFS9 / 42426
• FlyBaseID: FBgn0038799
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_009333.1
• Gene: SEO1 / 851230
• SGDID: S000000062
• Length: 593
• Species: Saccharomyces cerevisiae
• Alignment Length: 550
• Identity: 103/550 - (18%)
• Similarity: 178/550 - (32%)
• Gaps: 168/550 - (30%)

  Fly     6 SPKNGKHLE----QVHQNNNEIT-------ESEPLTWRFWRKQRYIV------------------ 41
            |.|:..|.|    ..|::|..:|       |::...|||:.:|.|.:
Yeast    60 SEKDQLHFETSSYSEHKDNVNVTRSYEYRDEADRPWWRFFDEQEYRINEKERSHNKWYSWFKQGT 124

  Fly    42 ------------VLLAFF---GFFNVYSLRVNLSVAIVAMTENRTVFDAD-----------GNVS 80
                        |||||:   .::..|...||::.|.|:..:....|..:           ||:.
Yeast   125 SFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNII 189

  Fly    81 YQQDFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAA-SHS 144
            :|..|.       :.|:.....|:|...                     ....:|||..|| .:|
Yeast   190 FQLPFL-------IYLNKLPLNYVLPSL---------------------DLCWSLLTVGAAYVNS 226

  Fly   145 LEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKY- 208
            :.....:|...|.||..::.....::..:....|..|.::..:.|.|.|.:.|   .|..:..|
Yeast   227 VPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSA---GGIQSAVYS 288

  Fly   209 ---------GWESVFYVFGTIGVIWYITWLVFVKAGPE--LDRFCSKEECDYIQKTI--GYVGSK 260
                     ||...|.:...:.|:..:.....:...|.  ...|.:.:|....:|.:  ...|..
Yeast   289 SLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKS 353

  Fly   261 HVKHP------WRAIFTSMPFYAIMA--------SHFSENWGFYTLLTQLPSFLRDTLNFDLGKT 311
            ..:..      |:.||:....|.:..        |:.|.  |.|.|      :|:....:.:.|.
Yeast   354 DFETKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSS--GAYLL------WLKSLKRYSIPKL 410

  Fly   312 GILSAV-PYLAMGILLAVSGYLAD-----WL-----QVKGI--------WTTTQVRRNFNCGAFL 357
            ..||.: |.|.| :.|.::|.:||     |.     ||..|        |...:..:.|   ||:
Yeast   411 NQLSMITPGLGM-VYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWF---AFM 471

  Fly   358 AQTVFMMLTAYLLDPTW--------------SVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVL 408
            .|.....:...|.  :|              ::|::.| :...:.||....|...:.||::..
Yeast   472 LQCFGWAMAPVLY--SWQNDICRRDAQTRAITLVTMNI-MAQSSTAWISVLVWKTEEAPRYLK-- 531

  Fly   409 MGIGNTFATIPGIVSPLLTGYVVTNQTSDE 438
               |.||.........:.|..|:.....||
Yeast   532 ---GFTFTACSAFCLSIWTFVVLYFYKRDE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	MFS_SLC17	43..461	CDD:340876	88/471 (19%)
SEO1	NP_009333.1	MFS_FEN2_like	134..548	CDD:340885	86/464 (19%)