Protein Alignment MFS9 and FEN2

DIOPT Version :10

• Sequence 1: NP_650889.1
• Gene: MFS9 / 42426
• FlyBaseID: FBgn0038799
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_009957.1
• Gene: FEN2 / 850394
• SGDID: S000000623
• Length: 512
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 107/526 - (20%)
• Similarity: 165/526 - (31%)
• Gaps: 190/526 - (36%)

  Fly     8 KNGKHLEQVHQNNNEITESEPLTWRFWRKQRYIVVLLAFF-----------------GFFNVYSL 55
            |..|.:.| |:...|...|:...     |:|.::..:..|                 ||.|.|
Yeast     3 KESKSITQ-HEVERESVSSKRAI-----KKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAY-- 59

  Fly    56 RVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGN 120
                   |..|.|:..:...|..||.                        |.|:.|||...:..|
Yeast    60 -------ISGMKEDLKMVGNDLTVSN------------------------TVFMIGYIVGMVPNN 93

  Fly   121 IV--------------FGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWA 171
            ::              |..|     :|||  .|....|.:....:|..:..||..||.|.|.|..
Yeast    94 LMLLCVPPRIWLSFCTFAWG-----LLTL--GMYKVTSFKHICAIRFFQALFESCTFSGTHFVLG 151

  Fly   172 RWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKY-----------GWESVFYVFGTIGVIWY 225
            .|... :...:.|..|.|  :|.|.:| .|||:.|..           ||..:|.:...|.:...
Yeast   152 SWYKE-DELPIRSAIFTG--SGLVGSM-FSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIA 212

  Fly   226 ITWLVFVKAGPELDRFCSK----------EECDYIQKTIGYVGSKHVKHPWRAIFTSMPFYAIMA 280
            |...:|....|:.....||          :|..|.::.:          |.|...|.:.:..|..
Yeast   213 IYGFIFFPGLPDQTSAVSKFSMTRYIFNEQELHYARRRL----------PARDESTRLDWSTIPR 267

  Fly   281 SHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTT 345
            .....:|..::|:..|..   :.|.|                    |.:...|.|||.:. :|..
Yeast   268 VLKRWHWWMFSLVWVLGG---ENLGF--------------------ASNSTFALWLQNQK-YTLA 308

  Fly   346 QVRRNFNCGAFLAQTVFMMLTAYLLDPT-----W------SVVSLTIAV---------------- 383
            | |.|:..|.|....|..:.:|..:...     |      |:|.:.:||
Yeast   309 Q-RNNYPSGIFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVVFSAQ 372

  Fly   384 GLGAFAWSGFAV--------NHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWR 440
            .||..|::|.||        .|.|:  |..::::...|.|:   |.|:..             |.
Yeast   373 YLGGVAYAGQAVFFSWANIICHADL--QERAIVLASMNMFS---GAVNAW-------------WS 419

  Fly   441 IIFFIS 446
            |:||.|
Yeast   420 ILFFAS 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	MFS_SLC17	43..461	CDD:340876	99/491 (20%)
FEN2	NP_009957.1	MFS_FEN2_like	32..450	CDD:340885	99/491 (20%)