DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and slc17a5

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	453	Identity:	194/453 - (42%)
Similarity:	279/453 - (61%)	Gaps:	26/453 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RYIVVLLAFFGFFNVYSLRVNLSVAIVAMT-------ENRTVFDADGNV-------------SYQ 82
            ||.:.|:|..|||.:|:||||||||:|.|.       ||.|     .|:             |..
Frog    40 RYNLALMALLGFFMLYALRVNLSVALVDMVNSTSTPRENTT-----ANICPDHTSAPAVLHNSTG 99

  Fly    83 QDFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEM 147
            |.:.||:..:|.||.||||||||||..|||:..||||..:.|.||..||:.|||||:||......
Frog   100 QKYDWDANTQGWILGSFFYGYILTQIPGGYVAGKIGGKQLLGFGILGTAVFTLLTPLAADFGAGC 164

  Fly   148 FLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWES 212
            .:.||.:||..||||||.:||:||||:|||||||:.|:::||...||||::|.||.:.....|..
Frog   165 LIAVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLSLSYAGAQLGTVVSLPVSGLICYYMDWIY 229

  Fly   213 VFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKHPWRAIFTSMPFYA 277
            |||:|||:||:|:|.|...|...|:..|..:..|.:||..|:....|.....|..|:..|:|.:|
Frog   230 VFYIFGTLGVLWFIMWCFLVSDTPQSHRSITDSEKEYILYTLQNQLSYRKSVPCCAMMKSLPLWA 294

  Fly   278 IMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIW 342
            |:.:|||.||.||||||.||:::::.|.|:..:.|.|||:|||...:.:.::|.:||.|:.|...
Frog   295 IIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQENGFLSALPYLGCWVFMIMAGVIADCLREKLNI 359

  Fly   343 TTTQVRRNFNCGAFLAQTVFMMLTAYL-LDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHAS 406
            :|..||:.||....|...:|::...|. .:.:.:||.||::..||.|:.:|:.:|||||||..|.
Frog   360 STKVVRKIFNTLGMLGPAIFLLAAGYTGCNYSLAVVFLTLSTTLGGFSVAGYGINHLDIAPSFAG 424

  Fly   407 VLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWA 469
            :|:||.||||||||:|.|::...:..:.|.::|:|:|:|:|.|...|.:.:..:.||::|:||
Frog   425 LLLGITNTFATIPGMVGPVIAKALTHDNTVEQWQIVFYIAAAINFFGAIFFIIFASGNVQDWA 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	194/453 (43%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	187/438 (43%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	184/427 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2916
SonicParanoid	1	1.000	-	-		X201
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030